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Sequential Site-Selective Functionalization: A Strategy for Total Synthesis of Natural Glycosides
Total synthesis of several ellagitannins, strictinin (1), pterocarinin C (2), cercidinin A (3), and tellimagrandin II (19), is described. The key... -
A Journey to the Total Synthesis of Brasilicardins
C(sp3)-rich natural products with quaternary carbon stereocenters have recently received increasing attention as formidable synthetic targets and... -
Total Synthesis of Avenaol
Avenaol is a terpene with a unique all-cis cyclopropane in which all bulky substituents are oriented in the same direction. It is categorized into a... -
Total Synthesis of Amycolamicin
Amycolamicin (also called kibdelomycin) produced by two species of soil actinomycetes is a potent antibiotic against a broad range of drug-resistant... -
Collective Total Synthesis of Secologanin-Related Natural Products
We have been interested in the reactivity of secologanin, which is transformed into more than 3000 natural products in nature and have been working... -
Medicinal Plants Against Herpes Simplex Virus (HSV) Type 1 Infections: Ethnopharmacology, Chemistry, and Clinical and Preclinical Studies
The use of medicinal plants as a remedy to various ailments is embedded in various cultures around the globe. However, the use of these treatments... -
Hepatitis C Virus (HCV) and the Role of Phytochemicals in the Anti-Viral Effects of Different Medicinal Plants Against Infection
Hepatitis C virus (HCV) infection causes acute as well as chronic inflammation in the liver. Its high prevalence with over 23.7 cases per 100,000... -
Respiratory Viral Infections and the Role of Medicinal Plants in Prevention and Treatment
Medicinal plants have a wide range of applications due to their efficacy, low side effects, and phytochemical substances that are effective in the... -
Anti-Viral Potential of Curcumins: Ethnopharmacology, Chemistry, and Clinical Studies Focusing on Mechanism of Action and Future Perspectives
Viruses have always been a serious public health concern, and scientists have worked diligently to make new anti-viral medicines. Virus infections... -
Gene Expression
During the normal functioning of living organisms, proteins are expressed according to well-regulated mechanisms to meet specific needs, this process... -
Regulatory Issues
The commercialisation and clinical use of biologicals is regulated in the USA by the FDA and in the EU by the EMA. -
Genomics and Pharmacogenomics
Advances in knowledge of genomics and proteomics have allowed the development of new biological products. For this purpose, the articulation of... -
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Medicinal Plants Against Human Adenovirus Type 1 Infections: Ethnopharmacology, Chemistry, and Clinical and Preclinical Studies
Adenoviruses are double-stranded DNA viruses responsible for respiratory infections, eye infections, epidemic conjunctivitis, and gastroenteritis in... -
Medicinal Plants in the Treatment of Influenza Virus A Infections: Role of Secondary Metabolites, Clinical and Preclinical Studies, and Future Perspectives
In the current period, respiratory diseases that evolved from influenza A infection have become a burning issue to the communities throughout the... -
Coumarins as Emerging Anti-Viral Compounds from Natural Origins: Ethnopharmacology, Chemistry, Mechanism of Action, Clinical and Preclinical Studies, and Future Perspectives
From the natural origin, more than 1300 coumarins have already been recognized. Coumarins are natural products and secondary metabolites in plants,... -
Gastrointestinal Viral Diseases and the Assessment of Effectiveness of Herbal Drugs in Prevention and Treatment
Viral gastroenteritis, usually a self-limiting disease condition, is one of the leading causes of morbidity and mortality all over the world,... -
Herbal Drugs and Medicinal Plants in Controlling and Treatment of Diseases Caused by Dengue Virus (DEN-1 & 2): Ethnopharmacology, Chemistry, and Clinical and Preclinical Studies
Dengue fever (DF) occurs worldwide and is a global health threat due to high mortality and morbidity, especially in tropical and subtropical regions.... -
Medicinal Plants in Controlling and Treatment of Diseases Caused by Viral Hemorrhagic Septicemia Virus (VHSV)
Numerous wild fish species around the world are affected by the viral hemorrhagic septicemia virus (VHSV), which is extremely contagious and... -
Traditional Plants in Controlling and Treatment of Fever, Joint Pain, and Pogosta Diseases Caused by Viruses
A mosquito-borne disease, pogosta, is clinically manifested by arthritis, rash, and fever. Its outbreak occur in 7-year intervals. Sindbis virus...