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Traditional Plants in Controlling and Treatment of Fever, Joint Pain, and Pogosta Diseases Caused by Viruses

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Anti-Viral Metabolites from Medicinal Plants

Part of the book series: Reference Series in Phytochemistry ((RSP))

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Abstract

A mosquito-borne disease, pogosta, is clinically manifested by arthritis, rash, and fever. Its outbreak occur in 7-year intervals. Sindbis virus (SINV) is considered as causative agent for this disease. Its suspected pathology and general mechanism are described in this chapter. Symptoms, molecular mechanisms, and its extensive investigation with plant species are broadly described here.

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Abbreviations

BBB:

Blood-brain barrier

CAMP:

Cyclic adenosine monophosphate

COX:

Cyclooxygenase

DMH:

Dorsomedial hypothalamus

IL:

Interleukins

LBP:

Lipopolysaccharide-binding proteins

LPS:

Lipopolysaccharides

PGE2:

Prostaglandin E2

POA:

Preoptic area

PVN:

Paraventricular nucleus

rRPa:

Medulla oblongata with rostral raphe pallidus nucleus

SINV:

Sindbis virus

TNF:

Tumor necrosis factor-α

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Acknowledgments

This work was supported by the Korean National Research Foundation (NRF-NRF, NRF – 2021R1F1A1048388, 2021R1F1A1063636).

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Authors and Affiliations

  1. Department of Pharmacology, Nityananda College of Pharmacy, Seragarh, Balasore, Odisha, India

    Tapas Kumar Mohapatra

  2. Mayurbhanj Medical Academy, Indapahi, Baripada, Mayurbhanj, Odisha, India

    Tara Shankar Basuri

  3. Department of Chemistry, Myongji University, Yoingin, Republic of Korea

    Dong Kee Yi & Sitansu Sekhar Nanda

  4. Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, Uttarakhand, India

    Supriyo Saha

  5. Department of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, India

    Dilipkumar Pal

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  1. Tapas Kumar Mohapatra
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  2. Tara Shankar Basuri
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  3. Dong Kee Yi
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  4. Supriyo Saha
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  5. Dilipkumar Pal
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  6. Sitansu Sekhar Nanda
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Correspondence to Dong Kee Yi .

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  1. Department of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur, India

    Dilipkumar Pal

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Mohapatra, T.K., Basuri, T.S., Kee Yi, D., Saha, S., Pal, D., Nanda, S.S. (2024). Traditional Plants in Controlling and Treatment of Fever, Joint Pain, and Pogosta Diseases Caused by Viruses. In: Pal, D. (eds) Anti-Viral Metabolites from Medicinal Plants. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-031-12199-9_25

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