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    Chapter

    Factors Affecting Formation and Structure of DNA Intrastrand Cross-Links by Dinuclear Platinum Complexes

    Dinuclear platinum complexes are currently undergoing pre-clinical evaluation. The development of this series has been driven by the hypothesis that a different spectrum of antitumor activity in comparison to ...

    Y. Qu, M. J. Bloemink, K. J. Mellish… in Cytotoxic, Mutagenic and Carcinogenic Pote… (1997)

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    Chapter and Conference Paper

    Bis(Platinum) Complexes. Chemistry, Antitumor Activity and DNA-Binding

    Bis(platinum) complexes of general formula [PtXnL3-n 2(diamine)](2-n)+ (X = for example CI, L = for example NH3, n = 1,2, and where diamine is most generally represented as H2N-R-NH2, with R a linea...

    J. D. Hoeschele, A. J. Kraker, Y. Qu… in Molecular Basis of Specificity in Nucleic … (1990)