6 Result(s)
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Chapter
Ulrich Laufs
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Chapter
Herz und Gehirn
Erkrankungen des Gehirns (z. B. der Schlaganfall) haben häufig kardiale Ursachen. Kardiologische Erkrankungen (z. B. die Herzinsuffizienz) können zu Veränderungen der Gehirnfunktion führen. Umgekehrt können ps...
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Kardiale Komorbidität – Möglichkeiten und Grenzen der perioperativen Konditionierung
Die fortschreitende Alterung der Bevölkerung führt zu steigenden Anforderungen an das perioperative Management, da mit zunehmendem Alter auch die Anzahl und die Komplexität der Komorbiditäten zunimmt. Das post...
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Long Noncoding RNAs in Cardiovascular Diseases
A major part of the human transcriptome consists of long noncoding RNAs (lncRNAs). These are RNA molecules longer than 200 nucleotides that do not contain open reading frames but can have a multitude of regula...
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Circular RNA Splicing
Circular RNAs (circRNAs) are covalently closed single-stranded RNA molecules derived from exons by alternative mRNA splicing. Circularization of single-stranded RNA molecules was already described in 1976 for ...
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Statins and Ezetimibe
In 1929, Schoenheimer reported that mammals not only synthesize cholesterol de novo but also absorb dietary cholesterol from the intestine while excluding dietary plant sterols [1]. Both dietary cholesterol co...
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Antioxidative Properties of Statins in the Heart
The overall benefits observed with the lipid-lowering HMG-CoA reductase inhibitors (statins) appear to be greater than might be expected from changes in lipid levels alone; and the positive effects have only p...
