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Chapter and Conference Paper
Indikationsbereiche von Klasse-I-Antiarrhythmika — differentialtherapeutische Aspekte bei ventrikulären Herzrhythmusstörungen
Während Anfang der achtziger Jahre die prognostische Bedeutung ventrikulärer Arrhythmieformen als weitgehend gesichert angesehen und eine entsprechende antiarrhythmischen Therapie verhältnismäßig freizügig geh...
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Chapter and Conference Paper
Calcium Antagonists in Silent Myocardial Ischemia — Preliminary Results with Nisoldipine
The use of calcium channel blockers was shown to be effective in the treatment of symptomatic and, more recently, of asymptomatic myocardial ischemia. In this continuing study we evaluated the efficacy of niso...
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Chapter
Grundlagen der Wirkung sympathikomimetischer Stoffe
Im nachfolgenden Kapitel werden zunächst einige für die klinische Praxis relevante Wirkungen sympathikomimetischer Stoffe an Organsystemen beschrieben und entsprechend ihren Angriffsorten eingeteilt und charak...
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Chapter and Conference Paper
Akutwirkungen der neuen inotropen Substanz OPC-8212
In den letzten Jahren sind zahlreiche inotrop wirkende Pharmaka zur Therapie der Herzinsuffizienz entwickelt worden [5]. Aus klinischer Sicht sind besonders diejenigen Substanzen von Interesse, welche für die ...
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Chapter
Echocardiographic Studies in Cardiomyopathies
Cardiomyopathies comprise a large and inhomogenous group of myocardial diseases. The term primary cardiomyopathy has been proposed for those cases in which a causal factor could not be found.
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Chapter
Isosorbide Dinitrate: Pharmacokinetics After Intravenous Administration
Isosorbide dinitrate (ISDN) is an important organic nitrate found therapeutically useful in its sublingual and oral forms in various cardiovascular diseases such as angina pectoris (1) and congestive heart fai...
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Chapter
Computertomographic Findings in Congestive Cardiomyopathy
The contribution of non-invasive radiologic diagnostic procedures has thus far been rather insignificant in the diagnosis of cardiomyopathy. The mainstay has been the conventional chest X-ray. Estimation of di...
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Chapter
Prevalence of Arrhythmias During 24-Hour Electrocardiographic Monitoring in Patients with Dilative Cardiomyopathy
Clinical symptoms of dilative (congestive) cardiomyopathy (DCM) were generally attributed to left ventricular pump failure or thromboembolic complications. Only sporadic reports appeared documenting arrhythmia...
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Chapter
Repetitive Response to Ventricular Extrastimuli in Patients with Dilated Cardiomyopathy
In dilated cardiomyopathy ventricular arrhythmias are frequently observed and may lead to sudden death from ventricular fibrillation [2, 3, 5]. Increased ventricular vulnerability therefore seems to exist in s...
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Chapter
Biochemical Findings in Serum of Patients with Congestive Cardiomyopathy: Is Serum Selenium Concentration a Possible Marker?
The conventional methods of clinical chemistry, such as determination of enzyme activities in serum, are not suited for diagnosis or differential diagnosis of cardiomyopathy. Only in a few cases have we observ...
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Chapter
Anticoagulant Activity of the Enantiomers of Acenocoumarol in Man
For the mono-coumarin derivatives warfarin and phen-procoumon it was shown that in man and rats the S(−) enantiomer is several times more potent as anticoagulant than the R(+) enantiomer. These stereoselective...
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Chapter
Über den Einfluß von Mangan-Ionen auf die positiv inotrope Wirkung von Adrenalin, Theophyllin und Digitoxigenin an isolierten Meerschweinchenvorhöfen
The influence of bivalent manganese ions (Mn++ ) on the positive inotropic effect of adrenaline, theophylline, and digitoxigenin was studied in isolated, electrically driven left guinea-pig auricles in phosphate-...