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    Chapter

    Integrins in Cancer: Refocusing on the Tumor Microenvironment

    Despite having been characterized for several decades, the development of therapeutically useful compounds based on integrins has shown little success. In cancer biology, previous studies mainly focused on the...

    Cédric Zeltz, Ning Lu, Ritva Heljasvaara… in The Extracellular Matrix and the Tumor Mic… (2022)

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    Chapter

    Experimental Tumour Models in Mice

    The complex multistage processes of tumour initiation, progression and metastasis challenge the methods that are used in basic cancer biology research and anticancer drug development. Experimental tumour model...

    Ritva Heljasvaara, Taina Pihlajaniemi in Mouse as a Model Organism (2011)