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    Chapter

    Polymorphic Variation and Risk of Colorectal Cancer

    Colorectal cancer (CRC) is the third commonest cancer worldwide after lung and breast cancer, and two-thirds of CRCs occur in developed countries [1, 2]. Despite recent advances in treatment the prognosis for CRC...

    Richard A. Hubner, Richard S. Houlston in Hereditary Colorectal Cancer (2010)

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    Chapter

    Genetics and the common cancers

    The importance of inherited predisposition is now established for a number of common cancers and the mechanisms by which mutations in some genes leads to cancer are at least partially understood. The ability t...

    Richard S. Houlston, Julian Peto in Genetic Predisposition to Cancer (1996)

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    Chapter

    Use of DNA technology in the diagnosis of occult atherosclerotic disease

    Cardiovascular disease (CVD) is a major contributor to mortality in western industrialised countries [1]. Its principle cause is atherosclerosis, with clinical effects only becoming apparant after years of asy...

    Richard S. Houlston, Steve E. Humphries in Occult Atherosclerotic Disease (1991)