44 Result(s)
within
English
Biomedicine
Molecular Medicine
Pharmacology/Toxicology
Qi** Li
Chapter
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Chapter
Unique Features of the Human Sinoatrial Node Structure, Function, and Arrhythmias: Mechanistic Insights from Integrated 3D Map** Approaches
The sinoatrial node (SAN) is the primary pacemaker in mammalian hearts, which generates intrinsic electrical activation to maintain synchronous and rhythmic contractility of the heart. Impairments in SAN struc...
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HDL and Therapy
A wealth of evidence indicates that high-density lipoprotein assumes the unique antiatherosclerosis and other cardioprotective properties. Based on that, HDL-C has been considered as a promising therapy target...
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Hot and Cold Theory: A Personalized Medicine Approach
The hot and cold theory is an important part of Traditional Medicines (TMs) which can be used in health care, disease prevention, diagnosis, and treatment purposes. However, little has been said about the mate...
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Comprehensive Prevention and Control of Coal-burning Type of Endemic Fluorosis
Coal-burning type of endemic fluorosis is an endemic fluorosis unique to China. In addition to the environmental factors, its prevalence and control are closely related to the social and economic development, ...
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Stress and Inflammation
Both stress and inflammatory responses play a key role in maintaining homeostasis in the body. Stress responds to threats while inflammation responds to injury and infection by some physiological mechanisms in...
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Autophagy in Cellular Stress Responses
Autophagy is an essential cellular mechanism involving the lysosomal degradation of cytoplasmic organelles or cytosolic components. Autophagy can be induced by various stress stimuli including oxidative stress...
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Epidemic Status of Coal-burning Type of Endemic Fluorosis
Fluoride gains its access to human body through digestive and respiratory tracts and then is excreted from kidney and widely found in hard tissues like bones and teeth, which are rich in calcium and phosphorus...
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Researches and Application of Ganoderma Spores Powder
Ganoderma lucidum spores (GLS) are the mature germ cells of Ganoderma lucidum. They have all the genetic substances and similar active components of Ganoderma lucidum. Similar to the fruiting body of Ganoderma lu...
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Protective Effect of Ganoderma (Lingzhi) on Radiation and Chemotherapy
Radiation and chemotherapy are common and mainstay treatments for cancer patients. But they are also usually associated with some toxicity and side effects in most of the patients. Ganoderma (Lingzhi) is consider...
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Molecular Identification of Traditional Medicinal Materials
Traditional medicines are consumed by 80% of the population in the world for health maintenance and disease treatment. The adulteration and substitution of source materials are life-threatening problems that h...
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Development and Innovation of Ganoderma Industry and Products in China
Ganoderma (Lingzhi) has been used as a medicinal mushroom to promote health in China for more than 2000 years. The modern research and development of Ganoderma industry started from the 1950s, in which the suc...
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Gene Modification of Medicinal Plant Germplasm Resources
Germplasm resources refer to the basic materials for selecting and cultivating new species, which include propagating materials of cultivated species and wild species from different plants and artificially cre...
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DNA Methylation Analysis Reveals a Strong Connection Between Tobacco Smoking and Cancer Pathogenesis
Tobacco smoking is a well-documented risk factor for various cancers, especially those of the lung. To test our hypothesis that abnormal DNA methylation loci associated with smoking are enriched in genes and p...
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Grand Challenges and Opportunities for Psychiatry, Including Nicotine Addiction Research
Psychiatric genetics is a new and promising field that may reveal what genetic variants are responsible for the development of a psychiatric disorder and enable customization of drug treatment for patients wit...
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Management, Pharmacotherapies, and Precision Medicine for Smoking Cessation
Although 70% of smokers want to quit, only 4–7% are successful in the long term. Cigarette smoking persists because of both the addictive propensity of nicotine and the low success rates of existing treatments...
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The Prevalence of Smoking and Its Associated Diseases
Smoking is the leading risk factor for several serious diseases and causes an enormous economic burden for the individual and society. Approximately six million deaths in the world annually are attributable to...
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Estimation of Genetic and Environmental Contributions to Smoking Addiction
Many studies of twins have shown that genetic and environmental factors play significant, and approximately equal, roles in the determination of smoking initiation (SI) and persistence (SP). Estimates of herit...
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Genetic Contribution of Variants in GABAergic Signaling to Nicotine Dependence
Although genetics contributes significantly to tobacco smoking, the susceptibility genes and variants underlying this behavior remain largely unknown. Genome-wide linkage and association studies have implicate...
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Significant Contribution of Variants in Serotonin Transporter and Receptor Genes to Smoking Dependence
Although genetics contributes significantly to smoking addiction, the susceptibility genes and variants underlying it remain largely unknown. Many years of genome-wide and candidate gene-based association stud...
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Background, Biology and Health Concerns of Electronic Cigarettes
Electronic cigarettes (ECIGs) are growing in popularity while generating worries on the part of lawmakers, healthcare providers, and smokers. Although ECIGs supposedly are a safe alternative to tobacco smoking...
