6 Result(s)
within
Chapter
Peter H. Wiernik
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Chapter
Novel biologic approaches to hematologic malignancies
Normal hematopoiesis and lymphopoiesis are dependent upon the interactions of a broad array of endogenous cytokines that have both positive and negative influences on proliferation and differentiation of these...
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Chapter
Expression of the Multidrug-Resistance Gene Product, P-Glycoprotein, In Adult Acute Myeloid Leukemia
Response-driven retrospective analysis of 382 adult ECOG patients with de novo AML for prognostically significant antigen profiles revealed that expression of P-glycopro-tein (Pgp) by >36.5% of blast cells predic...
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Chapter
Taxol: A new agent active in melanoma and ovarian cancer
Taxol was isolated in 1971 from the stem bark of the plant Taxus brevifolia, (western yew), a small evergreen native to the Pacific Northwest, and its structure was characterized by Wani et al. [l]. This drug is ...
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Chapter and Conference Paper
Recent Advances in Chemotherapy for Certain Leukaemias
Major advances in the chemotherapy of some leukaemias have recently been achieved. Although new combinations of established agents have contributed to these advances, the discovery of new agents with major an-...
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Chapter
The Therapy of Adult Acute Lymphoblastic Leukemia
Although acute lymphoblastic leukemia (ALL) is predominantly a childhood disease, adult ALL accounts for approximately 15% of all cases of adult acute leukemia [1]. In children, major progress has been achieve...
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Chapter
Current Issues in the Management of Patients with Hodgkin’s Disease
There is currently great and often heated debate over some important aspects of the management of patients with Hodgkin’s disease. New data concerning the proper staging of patients have been developed at seve...
