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    Challenges and Opportunities for Oligonucleotide-Based Therapeutics by Antisense and RNA Interference Mechanisms

    Oligonucleotide-based therapeutics may be one of the most promising approaches for the treatment of diseases. Although significant progress has been made in develo** these agents as drugs, several hurdles re...

    Ramon Eritja, Montserrat Terrazas, Santiago Grijalvo… in Chemical Biology of Nucleic Acids (2014)