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    Chapter

    Biochemical Studies of Class Switch Recombination

    Higher eukaryotes produce immunoglobulins (lg) of different classes, which are defined by the constant region (C) of the heavy chain. In the mouse the heavy chains are designated μ, δ, γ3, γ1, γ2b, γ2a, ε and ...

    Rolf Jessberger, Matthias Wabl… in Molecular Analysis of DNA Rearrangements i… (1996)

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    Chapter

    Somatic Hypermutability

    In his book “What is life?” which was so influential at the tinne, Erwin Schrödinger (1944) mused, “In orderte be suitable material for the work of natural selection, mutations must be rare events.” That is, stab...

    Matthias Wabl, Charles Steinberg in Molecular Analysis of DNA Rearrangements i… (1996)

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    Chapter

    Die genetische Grundlage der Antikörpervielfalt

    Thukydides beschreibt eine nicht identifizierte Seuche, die Athen im Peloponesischen Krieg (430 v. Chr.) heimsuchte. Ein Viertel der Athener Landstreitkräfte starben. „Diejenigen, die sich von der Kr...

    Matthias Wabl in Neue Entwicklungen in der Dermatologie (1987)