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    Chapter and Conference Paper

    Hypoxic VDAC1: A Potential Mitochondrial Marker for Cancer Therapy

    Finding new therapeutic targets to fight cancer is an ongoing quest. Because of insufficiencies in tumor vasculature, cells often are exposed to a hostile microenvironment that is low in oxygen (hypoxic) and n...

    M. Christiane Brahimi-Horn, N. M. Mazure in Tumor Microenvironment and Cellular Stress (2014)

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    Chapter

    Hypoxia and Tumour Angiogenesis

    The hypoxia-inducible factor (HIF) is a well-known transcription factor recognized to play a key role in tumour angiogenesis through a cellular response to a low tissue oxygen concentration, a feature of a rap...

    M. Christiane Brahimi-Horn, Julie Laferrière, Nathalie Mazure… in Tumor Angiogenesis (2008)