380 Result(s)
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Chapter
Neural Oscillations and Multisensory Processing
Neural oscillations play a role in sensory processing by coordinating synchronized neuronal activity. Synchronization of gamma oscillations is engaged in local computation of feedforward signals and synchroniz...
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Chapter
Adult Neurogenesis and Social Behavior: A Reciprocal Relationship
Neural plasticity refers to the brain’s life-long capacity to change itself functionally and structurally. Specifically, adult neurogenesis—a unique type of plasticity—has been a focus within the last decades ...
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Multisensory Integration in Body Representation
To be aware of and to move one’s body, the brain must maintain a coherent representation of the body. While the body and the brain are connected by dense ascending and descending sensory and motor pathways, re...
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Chapter
Cognitive Reserve: A Life-Course Perspective
The concept of reserve has been developed to account for the discontinuity between the extent of brain damage at its clinical manifestation in the form of cognitive decline or dementia. In this chapter, we dis...
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Chapter
Correction to: Tools and Model Systems to Study Nerve-Cancer Interactions
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Chapter
An Overview
Nowadays, China has rapidly progressed into an aging society and is faced with huge challenges on public health. Aging is accompanied by the structural and functional alterations in the brain, which leads to t...
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Plasticity of the Cerebellum
Since 1990s, long-term depression of (LTD) at parallel fiber–Purkinje cell synapses has been regarded as a cellular phenomenon for motor learning. However, parallel fiber LTD by itself cannot account for motor...
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Chapter and Conference Paper
Enhanced S-cone Syndrome, a Mini-review
Enhanced S-cone Syndrome (ESCS) is an autosomal recessive inherited retinal disease mostly associated with disease-causing variants in the NR2E3 gene. During retinal development in ESCS, rod photoreceptor precurs...
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Chapter and Conference Paper
Retinal Metabolic Profile on IMPG2 Deficiency Mice with Subretinal Lesions
The interphotoreceptor matrix (IPM) is the extracellular matrix between the photoreceptors and the retinal pigment epithelium (RPE). The IPM has two proteoglycans: the IPM proteoglycans 1 and 2 (IMPG1 and IMPG...
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Vascular Supply and Territories of the Cerebellum
Within the posterior circulation, Caplan and colleagues characterized brain and vascular structures as involving the proximal, middle, and distal posterior circulation territories. The proximal intracranial poste...
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Chapter
RETRACTED CHAPTER: Co-administration of Nanowired DL-3-n-Butylphthalide (DL-NBP) Together with Mesenchymal Stem Cells, Monoclonal Antibodies to Alpha Synuclein and TDP-43 (TAR DNA-Binding Protein 43) Enhance Superior Neuroprotection in Parkinson’s Disease Following Concussive Head Injury
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Chapter and Conference Paper
Current Advancements in Mouse Models of Retinal Disease
The field of retinal degenerative (RDs) disease study has been in a state of exponential growth from discovering the underlying genetic components of such diseases as age-related macular degeneration (AMD) and...
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Chapter and Conference Paper
Methods for In Vivo Characterization of Proteostasis in the Mouse Retina
An increasing number of studies connect inherited and age-related retinal degenerations with changes in the regulation of proteostasis. Here, we describe technical aspects of existing assays allowing to assess...
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RETRACTED CHAPTER: Co-administration of Nanowired Oxiracetam and Neprilysin with Monoclonal Antibodies to Amyloid Beta Peptide and p-Tau Thwarted Exacerbation of Brain Pathology in Concussive Head Injury at Hot Environment
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Cognitive Decline Associated with Aging
Cognitive decline is one of the most distinct signs of aging, and age-related cognitive decline is a heterogeneous issue varying in different cognitive domains and has significant differences among older adult...
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Chapter
iPSCs-Based Therapy for Trabecular Meshwork
The trabecular meshwork (TM) of the eye serves as an essential tissue in controlling aqueous humor (AH) outflow and intraocular pressure (IOP) homeostasis. However, dysfunctional TM cells and/or decreased TM c...
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Biomolecular Markers of Brain Aging
Characterized by the gradual loss of physiological integrity, impaired function, and increased susceptibility to death, aging is considered the primary risk factor for major human diseases, such as cancer, dia...
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Chapter
In Vivo Non-linear Optical Microscopy as a Multidimensional Approach to Decipher Sensory Coding
Every type of sensation is mediated by diversified groups of sensory neurons, organized in multifaceted ensembles and complex temporal dynamics. It follows that understanding how sensory input is encoded requi...
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Chapter
Cardiac Disease Modeling with Engineered Heart Tissue
The rhythmically beating heart is the foundation of life-sustaining blood flow. There are four chambers and many different types of cell in the heart, but the twisted myofibrillar structures formed by cardiomy...
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Chapter
Regulation of Ryanodine Receptor-Dependent Neurotransmitter Release by AIP, Calstabins, and Presenilins
Ryanodine receptors (RyRs) are Ca2+ release channels located in the endoplasmic reticulum membrane. Presynaptic RyRs play important roles in neurotransmitter release and synaptic plasticity. Recent studies sugges...
