5 Result(s)
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Chapter
Kim Margolin
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Chapter
Effective Salvage Therapy for Refractory Disseminated Breast Cancer with 5-Fluorouracil and High-Dose Continuous Infusion Folinic Acid
Treatment options are limited for patients with disseminated carcinoma of the breast whose disease has progressed after therapy with standard chemotherapeutic programs (1). In fact, the usefulness of testing i...
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Fluorouracil and Leucovorin in Advanced Breast Cancer
It is clear from the studies summarized above that the combination of leucovorin and 5-FU can salvage 15–20% of heavily-pretreated patients with advanced breast cancer. In previously-untreated patients, the co...
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Targeting Vascular Endothelium with Antibodies
Despite the recent progress in the management of cancer, the majority of metastatic solid tumors are not curable by current treatment modalities. In 1996 in the United States alone 500,000 people died as a res...
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Cytokines in the Treatment of Cancer
Cytokines are molecular mediators of intercellular signaling that function to regulate homeostasis of the immune system. There are five families of cytokines classified by their receptor usage. The effects of ...
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Melanoma
Rapid growth of translational research in the biology and immunology of melanoma has set the stage for improvements in therapy ranging from surgical procedures (reduced in extent, thus improving morbidity and ...
