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    Melanoma

    Rapid growth of translational research in the biology and immunology of melanoma has set the stage for improvements in therapy ranging from surgical procedures (reduced in extent, thus improving morbidity and ...

    Kathryn Bollin, Kim Margolin in Oncology in the Precision Medicine Era (2020)

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    Fluorouracil and Leucovorin in Advanced Breast Cancer

    It is clear from the studies summarized above that the combination of leucovorin and 5-FU can salvage 15–20% of heavily-pretreated patients with advanced breast cancer. In previously-untreated patients, the co...

    James H. Doroshow, Kim Margolin… in Novel Approaches to Selective Treatments o… (1993)

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    Effective Salvage Therapy for Refractory Disseminated Breast Cancer with 5-Fluorouracil and High-Dose Continuous Infusion Folinic Acid

    Treatment options are limited for patients with disseminated carcinoma of the breast whose disease has progressed after therapy with standard chemotherapeutic programs (1). In fact, the usefulness of testing i...

    James H. Doroshow, Lucille Leong… in The Expanding Role of Folates and Fluoropy… (1988)