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    Chapter

    Low matrix metalloproteinase levels precede vascular lesion formation in the JCR:LA-cp rat

    Clinically significant occlusive vascular lesions contain more extracellular matrix (ECM) proteins and lipid deposition than healthy vascular tissue. The events leading to this condition remain unresolved. One...

    David Wilson, Hamid Massaeli in Biochemistry of Diabetes and Atheroscleros… (2003)

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    Chapter

    Cardiovascular disease in the JCR:LA-cp rat

    The JCR:LA-cp rat is one of a number of strains that carry the mutant autosomal recessive cp gene. Animals, of all strains, that are homozygous, for the gene (cp/cp) become obese, insulin resistant, and hypertrig...

    James C. Russell, Sandra E. Graham in Molecular and Cellular Effects of Nutritio… (1998)

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    Chapter

    Age- and sex-related differences in nuclear lipid content and nucleoside triphosphatase activity in the JCR:LA-cp corpulent rat

    The putative role of the nuclear nucleoside triphosphatase (NTPase) is to provide energy to the nuclear pore complex for poly A(+) mRNA export. Previous work has demonstrated that liver nuclear NTPase activity...

    Michael P. Czubryt, James C. Russell in The Cellular Basis of Cardiovascular Funct… (1997)