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  1. No Access

    Chapter

    Reversal of Ethanol Tolerance and Cross-Tolerance to Pentobarbital in the Rat

    Adult male Wistar rats were fed nutritionally adequate liquid diets providing 35% of the total calories as ethanol, while pair-fed controls received the corresponding diet with ethanol replaced by an equicalor...

    J. M. Khanna, H. Kalant, A. D. Lê… in Alcohol and Aldehyde Metabolizing Systems-… (1980)

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    Chapter

    Cross-Tolerance between Ethanol and Morphine

    Adult male Wistar rats were fed chronically a liquid diet providing 35% of the calories as ethanol (10–12 g/kg ethanol daily), while pair-fed controls received the corresponding diet with alcohol replaced by a...

    A. D. Lê, J. M. Khanna, H. Kalant… in Alcohol and Aldehyde Metabolizing Systems-… (1980)

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    Chapter

    Role of Serotonin (5-Ht) in Tolerance to Ethanol and Barbiturates

    Previously it has been shown that chronic administration of p-chlorophenylalanine (p-CPA), slowed the development of tolerance to ethanol, pentobarbital and cross-tolerance development to ethanol in rats chronica...

    J. M. Khanna, A. D. Le, H. Kalant, A. E. LeBlanc in Biological Effects of Alcohol (1980)

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    Chapter

    Alcohol Induced Susceptibility to Hypoxic Liver Damage: Possible Role in the Pathogenesis of Alcoholic Liver Disease?

    Previous studies in our laboratory (1–3), have indicated that the major rate limiting factor in ethanol metabolism in the intact liver cell is the rate of mitochondrial reoxidation to NAD+ of NADH produced in the...

    Y. Israel, H. Orrego, J. M. Khanna, D. J. Stewart, M. J. Phillips… in Alcohol and the Liver (1977)