111 Result(s)
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Chapter
Insoluble Proteins of the Synaptic Plasma Membrane
The presynaptic plasma membrane of a CNS neuron is that part of its limiting membrane that confines the terminal knob or bouton of its axonal process.(l, 2) Within the space defined by this structure are containe...
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Chapter
Carrier-Mediated Transport Processes
In Chapter 20(1) the movement of solutes across biological membranes is treated in relation to processes which do not, in general, involve a chemical interaction between the permeant and the membrane, and which a...
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Chapter
Abstracts of Submitted Papers
The mechanism of alcoholic hyperlipemia was studied in rats fed liquid diets with 36% of calories as ethanol or carbohydrate (controls). 3H was given intragastrically and 14C-lysine injected intravenously with or...
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Chapter
Fixation and tissue preservation for antibody studies
The methods of fixation and preparation of lymphoid tissues for the immunoenzyme technique are reviewed. For this technique an enzyme is used first as an antigen and then as a marker to demonstrate its specifi...
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Chapter
Lack of C3 Activation through Classical or Alternate Pathways by Human Secretory IgA Anti Blood Group a Antibody
There have been several reports showing that serum IgA antibody does not fix Cl or activate the complement sequence as judged by the classical hemolytic assay following aggregation of the molecule either by he...
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Chapter
Sequential Gene Expression in Response to Estradiol-l7β During Post-Natal Development of Rat Uterus
Hormonal model systems play an important role in the study of the control of protein synthesis (1) and of development (2). Thus the stimulation of nucleic acid and protein synthesis (3–5) in the immature rat u...
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Chapter and Conference Paper
Some Problems Concerning the Quantitative Assay of Primidone and Its Metabolites
All pharmacokinetic studies dealing with primidone therapy are complicated because phenobarbitone and phenylethylmalondiamide (PEMA) are the main metabolites of the biotransformation of primidone.
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Chapter
The Effect of Water, Sodium Overloading and Diuretics upon Urinary Kallikrein
Urinary kallikrein is significantly decreased in different types of experimental (Croxatto and San Martin, 1970; Margolius et al., 1972), clinical (Margolius. et al., 1972; Adetuyibi and Mills, 1972; Greco et ...
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Chapter
Metronidazole in the Treatment of Anaerobic Infection in Man
In recent years there has been a growing awareness of the importance of B. fragilis as a cause of human infections, in particular abdominal sepsis and cerebral abscess (Gillespie and Guy 1956; Ingham et al. 1968;...
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Chapter
Drug metabolism and pharmacokinetic studies in man utilising nitrogen-15- and deuterium-labelled drugs: the metabolic fate of cinoxacin and the metabolism and pharmacokinetics of propoxyphene
During the past several years, stable isotope utilisation has entered explosively into the clinical pharmacology laboratory for two major reasons: (1) the development of relatively simple, reliable instrumenta...
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Chapter
Hemodynamic Effects of Acute β-Adrenergic Blockage with Atenolol
8 healthy volunteers (age 25±4 years) received in randomized sequence 50, 100, 200, 400, and 600 mg Atenolol orally and 50 mg Atenolol intravenously during 5 minutes under continuous ECG monitoring. On 3 consecut...
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Chapter
Response of Renal Blood Flow and Renal Sympathetic Nerve Activity to Baroreceptor and Emotional Stimuli in the Conscious Dog
With respect to the nervous control of kidney blood flow, a traditional discrepancy is evident in the literature when the results of electrophysiologic studies are compared with those applying hemodynamic meas...
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Chapter
Dihydrodiol Dehydrogenase: An Important Enzyme in Dihydrodiol-Epoxide Pathway — Mediated Benzo(A)Pyrene Mutagenicity
Benzo(a)pyrene is metabolized to two major groups of mutagenically reactive metabolites: Monofunctional epoxides and dihydrodiol-epoxides. Various monooxygenase forms catalyze the various pathways at very diff...
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Chapter
Effects of Chenodeoxycholic Acid (CD) Treatment on Endogenous Plasma Triglyceride (TG) Transport in Hyperlipoproteinemia (HLP)
CD treatment inhibits hepatic cholesterol and bile acid formation. Preliminary reports suggest a plasma TG-lowering effect. This study was aimed at characterizing the alterations in TG concentration and turnov...
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Chapter
Separation of Earthworm Coelomocytes by Velocity Sedimentation
Earthworm leukocytes (coelomocytes) are heterogeneous morphologically (1,2) and participate in diverse functions including graft rejection (3), phagocytosis (1), formation of rosettes with SRBC (4), and mitoge...
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Chapter
Purification of Horse Renal Kallikrein and Chemical Relations with Horse Urinary Kallikrein
Kallikrein was purified from horse kidney by several steps of chromatographic procedure and by affinity chromatography on SepharoseConcanavaline. Horse urinary kallikrein was previously purified by DE-32 hydro...
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Chapter
Chemical Relations between Renal and Urinary Kallikrein of Rat
The ratio in μ-Moles between each aminoacid residue of both hydrolized renal and urinary kallikrein of rat, is about 1.00 ± 0.3. Except for Glu, His and Glucosamine a good proportion between all residues of bo...
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Chapter and Conference Paper
Amperometric — Enzymatic Analysis of Lactic Acid
Since the concentration of lactate in blood may vary rapidly, the usefulness of a lactate assay frequently depends on the speed of the analytical method. The enzymatic-amperometric technique described here off...
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Chapter and Conference Paper
Calibration Standards for Multi Ion Analysis in Whole Blood Samples
Several analytical devices on the market today are capable of determining various parameters in whole blood with the aid of ion-selective electrodes. These devices are generally suitable for use in intensive c...
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Chapter
Organization of Extrastriate Visual Areas in the Macaque Monkey
In primates, the regions of cerebral cortex that are specifically visual in function occupy the entire occipital lobe plus substantial portions of the temporal and parietal lobes. The division of the occipital...