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  1. No Access

    Chapter

    Insoluble Proteins of the Synaptic Plasma Membrane

    The presynaptic plasma membrane of a CNS neuron is that part of its limiting membrane that confines the terminal knob or bouton of its axonal process.(l, 2) Within the space defined by this structure are containe...

    H. R. Mahler, Carl W. Cotman in Protein Metabolism of the Nervous System (1970)

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    Chapter

    Carrier-Mediated Transport Processes

    In Chapter 20(1) the movement of solutes across biological membranes is treated in relation to processes which do not, in general, involve a chemical interaction between the permeant and the membrane, and which a...

    H. R. Wyssbrod, W. N. Scott, W. A. Brodsky in Metabolic Turnover in the Nervous System (1971)

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    Chapter

    Abstracts of Submitted Papers

    The mechanism of alcoholic hyperlipemia was studied in rats fed liquid diets with 36% of calories as ethanol or carbohydrate (controls). 3H was given intragastrically and 14C-lysine injected intravenously with or...

    E. Baraona, R. Pirola, C. S. Lieber in Pharmacological Control of Lipid Metabolism (1972)

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    Chapter

    Fixation and tissue preservation for antibody studies

    The methods of fixation and preparation of lymphoid tissues for the immunoenzyme technique are reviewed. For this technique an enzyme is used first as an antigen and then as a marker to demonstrate its specifi...

    H. R. P. Miller in Fixation in Histochemistry (1973)

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    Chapter

    Lack of C3 Activation through Classical or Alternate Pathways by Human Secretory IgA Anti Blood Group a Antibody

    There have been several reports showing that serum IgA antibody does not fix Cl or activate the complement sequence as judged by the classical hemolytic assay following aggregation of the molecule either by he...

    H. R. Colten, J. Bienenstock in The Immunoglobulin a System (1974)

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    Chapter

    Sequential Gene Expression in Response to Estradiol-l7β During Post-Natal Development of Rat Uterus

    Hormonal model systems play an important role in the study of the control of protein synthesis (1) and of development (2). Thus the stimulation of nucleic acid and protein synthesis (3–5) in the immature rat u...

    A. M. Kaye, Dalia Sömjen, R. J. B. King, G. Sömjen in Control of Gene Expression (1974)

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    Chapter and Conference Paper

    Some Problems Concerning the Quantitative Assay of Primidone and Its Metabolites

    All pharmacokinetic studies dealing with primidone therapy are complicated because phenobarbitone and phenylethylmalondiamide (PEMA) are the main metabolites of the biotransformation of primidone.

    H. R. Schäfer in Clinical Pharmacology of Anti-Epileptic Drugs (1975)

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    Chapter

    The Effect of Water, Sodium Overloading and Diuretics upon Urinary Kallikrein

    Urinary kallikrein is significantly decreased in different types of experimental (Croxatto and San Martin, 1970; Margolius et al., 1972), clinical (Margolius. et al., 1972; Adetuyibi and Mills, 1972; Greco et ...

    H. R. Croxatto, F. Huidobro, M. Rojas, J. Roblero, R. Albertini in Kinins (1976)

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    Chapter

    Metronidazole in the Treatment of Anaerobic Infection in Man

    In recent years there has been a growing awareness of the importance of B. fragilis as a cause of human infections, in particular abdominal sepsis and cerebral abscess (Gillespie and Guy 1956; Ingham et al. 1968;...

    J. B. Selkon, J. H. Hale, H. R. Ingham in Chemotherapy (1976)

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    Chapter

    Drug metabolism and pharmacokinetic studies in man utilising nitrogen-15- and deuterium-labelled drugs: the metabolic fate of cinoxacin and the metabolism and pharmacokinetics of propoxyphene

    During the past several years, stable isotope utilisation has entered explosively into the clinical pharmacology laboratory for two major reasons: (1) the development of relatively simple, reliable instrumenta...

    R. L. Wolen, B. D. Obermeyer, E. A. Ziege, H. R. Black, C. M. Gruber Jr. in Stable Isotopes (1978)

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    Chapter

    Hemodynamic Effects of Acute β-Adrenergic Blockage with Atenolol

    8 healthy volunteers (age 25±4 years) received in randomized sequence 50, 100, 200, 400, and 600 mg Atenolol orally and 50 mg Atenolol intravenously during 5 minutes under continuous ECG monitoring. On 3 consecut...

    J. Gerloff, G. Bodem, H. R. Ochs, M. Czypionka in Deutsche Pharmakologische Gesellschaft (1978)

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    Chapter

    Response of Renal Blood Flow and Renal Sympathetic Nerve Activity to Baroreceptor and Emotional Stimuli in the Conscious Dog

    With respect to the nervous control of kidney blood flow, a traditional discrepancy is evident in the literature when the results of electrophysiologic studies are compared with those applying hemodynamic meas...

    H. R. Kirchheim, R. Gross in The Arterial System (1978)

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    Chapter

    Dihydrodiol Dehydrogenase: An Important Enzyme in Dihydrodiol-Epoxide Pathway — Mediated Benzo(A)Pyrene Mutagenicity

    Benzo(a)pyrene is metabolized to two major groups of mutagenically reactive metabolites: Monofunctional epoxides and dihydrodiol-epoxides. Various monooxygenase forms catalyze the various pathways at very diff...

    P. Bentley, K. Vogel, H. R. Glatt, K. Platt in Deutsche Pharmakologische Gesellschaft (1978)

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    Chapter

    Effects of Chenodeoxycholic Acid (CD) Treatment on Endogenous Plasma Triglyceride (TG) Transport in Hyperlipoproteinemia (HLP)

    CD treatment inhibits hepatic cholesterol and bile acid formation. Preliminary reports suggest a plasma TG-lowering effect. This study was aimed at characterizing the alterations in TG concentration and turnov...

    B. Angelin, K. Einarsson, B. Leijd in Drugs, Lipid Metabolism, and Atheroscleros… (1978)

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    Chapter

    Separation of Earthworm Coelomocytes by Velocity Sedimentation

    Earthworm leukocytes (coelomocytes) are heterogeneous morphologically (1,2) and participate in diverse functions including graft rejection (3), phagocytosis (1), formation of rosettes with SRBC (4), and mitoge...

    E. L. Cooper, H. R. MacDonald, B. Sordat in Function and Structure of the Immune System (1979)

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    Chapter

    Purification of Horse Renal Kallikrein and Chemical Relations with Horse Urinary Kallikrein

    Kallikrein was purified from horse kidney by several steps of chromatographic procedure and by affinity chromatography on SepharoseConcanavaline. Horse urinary kallikrein was previously purified by DE-32 hydro...

    G. Porcelli, G. B. Marini-Bettolo, H. R. Croxatto, M. Di Jorio in Kinins—II (1979)

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    Chapter

    Chemical Relations between Renal and Urinary Kallikrein of Rat

    The ratio in μ-Moles between each aminoacid residue of both hydrolized renal and urinary kallikrein of rat, is about 1.00 ± 0.3. Except for Glu, His and Glucosamine a good proportion between all residues of bo...

    G. Porcelli, G. B. Marini-Bettòlo, H. R. Croxatto, M. Di Jorio in Kinins—II (1979)

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    Chapter and Conference Paper

    Amperometric — Enzymatic Analysis of Lactic Acid

    Since the concentration of lactate in blood may vary rapidly, the usefulness of a lactate assay frequently depends on the speed of the analytical method. The enzymatic-amperometric technique described here off...

    H. R. Wuhrmann in Lactate (1980)

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    Chapter and Conference Paper

    Calibration Standards for Multi Ion Analysis in Whole Blood Samples

    Several analytical devices on the market today are capable of determining various parameters in whole blood with the aid of ion-selective electrodes. These devices are generally suitable for use in intensive c...

    H. F. Osswald, H. R. Wuhrmann in Progress in Enzyme and Ion-Selective Electrodes (1981)

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    Chapter

    Organization of Extrastriate Visual Areas in the Macaque Monkey

    In primates, the regions of cerebral cortex that are specifically visual in function occupy the entire occipital lobe plus substantial portions of the temporal and parietal lobes. The division of the occipital...

    D. C. Van Essen, J. H. R. Maunsell, J. L. Bixby in Multiple Visual Areas (1981)

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