44 Result(s)
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Chapter
Allogeneic Hematopoietic Stem Cell Transplantation for AML
Acute myeloid leukemia (AML) is the main indication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Even with the great advances of targeted drugs in last decades, allo-HSCT is still the mos...
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Chapter
First-Line Systemic Treatment Options for Advanced Renal Cell Carcinoma
The treatment of advanced clear cell renal cell carcinoma (ccRCC) has undergone significant changes over the last two decades, particularly with the development of antiangiogenic therapies, in particular vascu...
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Chapter
Radiotherapy and Immunotherapy for Head and Neck Cancer
Immune checkpoint inhibitors (ICI) have revolutionized cancer treatment. However, although the immune landscape suggests a strong rationale for the use of these agents in patients with head and neck squamous c...
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Chapter
Palliative Radiotherapy
Palliative radiotherapy (RT) is a relative term, which refers to the use of RT in situations when it is impossible to completely eliminate all visible lesions. It contrasts with radical RT, in which the goal i...
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Nanoparticle-Based Phototherapy in Combination with Checkpoint Blockade for Cancer Immunotherapy
Cancer immunotherapy has demonstrated great therapeutic responses in clinic by educating and awakening patients’ own immune system to against cancer cells. Along with development of immunotherapy in preclinic ...
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Chapter
Cannabinoids and Child Development: During and After Pregnancy
With the recent increase in availability of medical marijuana and legalization of its use in multiple states, a growing number of the population are reporting recreational or regular use of marijuana. In pregn...
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Chapter
Cannabis Va** Hazards
E-cigarettes’ popularity in the United States began in 2007, and since then e-cigarette has become the mostly commonly used product among the youth. These va** devices were originally created for inhaling ni...
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Chapter
Ethics: Informed Consent, Patient Privacy
Molecular diagnostics has been dependent on genetic or genomic testing or other high-throughput omic technologies and progressed significantly by rapid advances of novel technologies and bioinformatics during ...
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Chapter
Digestive Tract Disease
Stomach, one of the body’s digestive system, is the expanding part of esophagus. The shape of the stomach can be affected by the state of fullness. When the stomach is completely empty, it is slightly tubular ...
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Chapter
Resilience in Pediatric Oncology
The focus on precision health in healthcare fits well with the recent shift from a traditional illness-focused model to a positive health approach. Precision health seeks to tailor treatment and supportive car...
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Chapter
Immunopathology as a Basis for Immunotherapy of Head and Neck Squamous Cell Carcinoma
Immunologic strategies to treat head and neck squamous cell carcinoma (HNSCC) have recently attracted new interest with the introduction of immunotherapy like checkpoint inhibitors into the clinical routine. S...
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Chapter
Molecular Imaging and Targeted Therapy in Neurology
As the most common motor neurodegenerative disorder, Parkinson’s disease has been the second most common neurodegenerative disorder after Alzheimer’s disease (AD). The prevalence of Parkinson’s disease (PD) is...
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Chapter
Gynecologic Tumor PET/CT Imaging
PET/CT is a mature noninvasive molecular imaging tool in modern oncology that can detect changes in tissue biology, and functional changes usually occur earlier than structural changes. PET/CT can also provide...
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Chapter
Surgical Therapy
A growing body of evidence suggests that early stage pT1 gastric cardiac cancer can be better resected endoscopically, but advanced, nonmetastatic resectable tumors without esophageal invasion or with esophage...
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Chapter
The HGF/MET Signaling and Therapeutics in Cancer
The Met proto-oncogene encodes MET tyrosine kinase protein which is a receptor for hepatocyte growth factor/scatter factor (HGF/SF). HGF binds to and activates MET to regulate diversified cellular and molecular a...
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Chapter
Palliative Care
Palliative care plays an increasingly important role in terminally ill patients with advanced gastric cardiac cancer. The most important task in palliative care is to reduce mental and physical suffering and h...
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Chapter
Met Activation and Carcinogenesis
MET is a tyrosine kinase receptor that transduces intracellular signaling to activate the MAPK, PI3K-Akt, and cadherin pathways (among others). In cancer cells, MET is activated upon stimulation by its only li...
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Chapter
Use of Nanomedicine in the Diagnosis of Gastric Cancer
Gastric cancer is one of the most common cancers and a leading cause of cancer related death worldwide. As to the diagnosis of gastric cancer, both regular systemic imaging and locoregional imaging are of grea...
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Chapter
Tumors of Extrahepatic Bile Duct
The rate of extrahepatic biliary benign tumors is very low, accounting for less than one tenth the rate of malignant biliary tumors, and the diameter of the tumor varies from several milimeters to centimeters;...
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Chapter
Tumors of the Gallbladder
Generalized polypoid lesions of the gallbladder (PLG) refer to all the protruding lesions on the mucosal surface of the gallbladder, the incidence of which is 3–7% in a healthy population and 2–12% in cholecys...
