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Chapter
Morbidity & mortality conferences — How can we do it?
Quality assurance is a very important aspect of daily life in a neurosurgical department as well as an important parameter for the neurosurgical patient. Quality assurance programmes of some sort are common bu...
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Chapter and Conference Paper
Shunting to the Sagittal Sinus
To develop a shunt that drains CSF from the ventricles to the sagittal sinus under normal-physiological conditions. This shunting principle will not lead to any over-drainage, and a large proportion of the kno...
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Chapter and Conference Paper
Computerized Infusion Test Compared to Conventional Lumbo-Ventricular Perfusion for Measurement of Resistance to CSF-Outflow
While it is generally agreed that measurement of resistance to outflow of CSF (Rout) is valuable in the diagnosis of diseases associated with disturbances in the CSF-dynamics, the invasive character and practical...
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Chapter
Current Concepts of Measurement of Cerebrospinal Fluid Absorption and Biomechanics of Hydrocephalus
New investigate methods have extended the scientific and clinical knowledge of the circulation of the cerebrospinal fluid (CSF). Methods of measurement of resistance to CSF outflow have improved during the las...
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Chapter
Absence of Hydrocephalus in Spite of Impaired Cerebrospinal Fluid Absorption and Severe Intracranial Hypertension
In the paper we have described four patients presenting papilledema, increased pressure and reduced CSF absorption, either caused by spinal tumours, leptomeningeal carcinomatosis or chronic encephalitis. All t...
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Chapter and Conference Paper
Brain Water Accumulation in Pseudotumour Cerebri Demonstrated by MR-imaging of Brain Water Self-Diffusion
We studied brain water self diffusion in pseudotumour cerebri by MR-imaging using single spin echo pulse sequences with pulsed magnetic field gradients of different magnitude. The methods is based on the fact ...
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Chapter
Resistance to Cerebrospinal Fluid Outflow and Intracranial Pressure in Patients with Hydrocephalus after Subarachnoid Haemorrhage
Resistance to CSF-outflow (Rout) and intracranial pressure (ICP) were measured in 33 patients with hydrocephalus after subarachnoid haemorrhage (SAH). Eleven patients examined between 10 to 30 days after SAH had ...
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Chapter and Conference Paper
The Acute Effect of Nimodipine on Intracranial Pressure and Cerebral Blood Flow
In acute stroke it has been shown that the calcium antagonist PY 108-068 induces a slight increase in mean cerebral blood flow (CBF) in some cases with a concomitant flow reduction in focal ischemic areas [8]....
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Chapter and Conference Paper
Concentrations of Neurotransmitters in Ventricular and Lumbar Cerebrospinal Fluid in Patients with Normal Pressure Hydrocephalus
For several years concentrations of neurotransmitters and their metabolites in lumbar cerebrospinal fluid have been used for diagnostic purposes or to elucidate the pathophysiology of disorders in the central ner...
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Chapter and Conference Paper
Measurement of Resistance to CSF Outflow — Clinical Experiences in 333 Patients
Increasing interest in pathological conditions due to possible impairment of CSF reabsorption has prompted a demand for a clinically usable, low risk and not too time-consuming method for measurement of resist...
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Chapter and Conference Paper
Comparison of Resistance to Outflow (Rout) Measured by Ventricular and Lumbar Perfusion
Several methods are available when studying the resorptive capacity of cerebrospinal fluid. In clinical practice, measurement of the resistance to CSF outflow (Rout) has been shown to be useful (Børgesen and Gjer...
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Chapter and Conference Paper
ICP, CSF Outflow Resistance and Brain Edema in Experimental Pneumococcal Meningitis
The mortality and morbidity of bacterial meningitis remain high. Clinical observations indicate that increased ICP and brain oedema are the main causes of adverse outcome.
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Chapter and Conference Paper
No Effect on ICP of ACE-Inhibition During Induced Hypotension
Experimental studies in rats have demonstrated that the angiotensin converting enzyme (ACE) inhibitor Captopril shifts the lower and upper limits of autoregulation of cerebral blood flow (CBF) towards lower bl...
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Chapter and Conference Paper
Different Time Course of Clinical Symptoms and CSF Dynamics in Patients with Pseudotumor Cerebri
Pseudotumor cerebri or benign intracranial hypertension is nearly uniformly reported to be a self-limiting disorder with an excellent long-term prognosis except for the occurrence of permanent visual loss in a...
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Chapter and Conference Paper
Increased Brain Water Self Diffusion Measured by Magnetic Resonance Scanning in Patients with Pseudotumor Cerebri
The pathophysiology of the intracranial hypertension in pseudotumor cerebri is still an unsolved puzzle. Increased resistance to CSF outflow leading to an increased CSF volume (interstitial brain edema) (Johns...
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Chapter and Conference Paper
CSF Production in Patients with Increased Intracranial Pressure
The relationship between intracranial pressure (ICP), resistance to CSF outflow (Rout), CSF formation rate (RF), and the pressure in the sagittal sinus (Pss) is generally accepted to be linear (Børgesen 1984, Eks...
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Chapter and Conference Paper
Reproducibility and Reliability of Measurement of Resistance to CSF Outflow by Subarachnoid Perfusion
It is generally agreed that the main site of CSF absorption is the arachnoid villi. The CSF resorptive capacity can be evaluated by several methods which, during the last decade, have been evaluated especially...
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Chapter
Prognosis of Dementia in Normal-pressure Hydrocephalus after a Shunt Operation
Dementia in NPH is a state which is generally accepted as being reversible after shunting. The reversibility is seldom demonstrated by adequate objective methods. In the present investigation 40 patients with ...
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Chapter and Conference Paper
Resistance to Cerebrospinal Fluid Outflow Following Subarachnoid Haemorrhage
Subarachnoid haemorrhage (SAH) often causes an increase in intracranial pressure (ICP) either by inpairment of the cerebrospinal fluid (CSF) resorption or by brain oedema (Kosteljanetz 1984, Voldby 1985). Fift...
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Chapter and Conference Paper
The Effect of Nimodipine on ICP and CBF in the Awake Patient
In human studies it has been shown that the calcium antagonist PY 108-068 induces a considerable increase in cerebral blood flow (CBF) with a concomitant flow reduction in focal ischemic areas [9]. In experime...
