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    Chapter

    Glucocorticoid Regulation of Cell Proliferation

    Initiation of DNA replication in non-embryonic cells requires passage through an irreversible step in late Gl that has come to be called the restriction point. The restriction point was originally defined as t...

    E. Aubrey Thompson in Steroid Hormones and Cell Cycle Regulation (2002)

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    Chapter

    TGF-β Inhibition of Intestinal Epithelial Cell Proliferation: G1 Cyclins, Cyclin-Dependent Kinases, and Cyclin Kinase Inhibitors

    Colon carcinogenesis is a multistep process involving alterations in the normal replication of intestinal epithelial cells Vogelstein et al., 1988; Cameron et al., 1990; Vogelstein, 1990. In recent years, ther...

    E. Aubrey Thompson, Tien C. Ko, R. Daniel Beauchamp in Hormones and Cancer (1996)