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Chapter
The Neuroprotective and Neuronal Rescue Effect of (-)-Deprenyl
(-)-Deprenyl treatment is able to increase the dopaminergic tone in the CNS by several mechanisms. It inhibits the normal metabolic degradation of dopamine and the metabolites formed from the drug reduce the u...
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Chapter
Modification of Pathobiological Events by Potential Hepatopharmacological Agents
The elucidation of the pathobiological events in chronic liver diseases — such as cellular injury, cell proliferation, remodelling of extracellular matrix — has considerable importance for establishing the rat...
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Chapter
Theoretical Bases for Designing Combination Therapy with Dibromodulcitol (DBD)
From the results of clinical and experimental tumour chemotherapy it seems that no single agent seems to be able to deal effectively with most of the human tumours and reasonable therapeutic results can only b...