15 Result(s)
within
Chapter
Akira Matsumura
-
Chapter
Electroneurophysiology and Brain Functional Imaging for Brain-Machine-Interface
Engineering is indispensable for the development of clinical devices. The devices are also utilized for basic neuroscience, brain-machine-interface (BMI) research, neuromodulation and so on. This paper will ou...
-
Chapter and Conference Paper
Decrease in the Apparent Diffusion Coefficient in Peritumoral Edema for the Assessment of Recurrent Glioblastoma Treated by Bevacizumab
Purposes: Anti-edema effect of bevacizumab was evaluated using the apparent diffusion coefficient (ADC) of peritumoral edema associated with regional cerebral blood flow (rCBV) of the tumor.
-
Chapter
Prevention of Vascular Restenosis After Vascular Angioplasty
Percutaneous transluminal angioplasty (PTA) and stenting are widely used methods for the treatment of vascular stenosis and much less invasive than surgery, but restenosis still occurs in 30–60 % of coronary a...
-
Chapter
Feasibility for Intramedullary Spinal Glioma
Spinal cord tumors are lesions that occur within or adjacent to the spinal cord. They are considered to be intra-axial in location and can be either primary or metastatic. Spinal cord tumors are relatively rar...
-
Chapter
Malignant Brain Tumors: Role of Radioresponsive Gene Therapy
Patients with malignant gliomas have a very poor prognosis. To explore a novel and more effective approach for the treatment of malignant gliomas, a strategy combining suicide gene therapy and radiation treatm...
-
Chapter
Clinical Protocol Using New Neutron Irradiation Facility (JRR4) at JAERI
After the shutdown of the former JRR2, which had been used for boron neutron capture therapy (BNCT) in clinical cases, in summer 1998 a new neutron irradiation facility (JRR4) was installed as a medical reacto...
-
Chapter
An Autopsy Report of a Glioblastoma Case after Boron Neutron Capture Therapy
Clinical trials of BNCT for glioblastoma have been underway around the World. In Japan, the new reactor JRR-4 has been now reconstructed especially for therapeutic irradiation. From the clinical point of view,...
-
Chapter and Conference Paper
Radiographic Results of Cemented Stem Revision in THA
Radiographic and clinical results of revision and rerevision total hip arthroplasties (THA) with cemented stem were reviewed over 2-year follow-up. Revision THA was performed in 57 hips at an average age of 61...
-
Chapter
In Vivo and In Vitro Uptake Study of Boronated Porphyrins for Neutron Capture Therapy
To improve boron neutron capture therapy (BNCT), a new tumor-seeking drug is required. Boronated porphyrins have been developed for boron carriers in boron neutron capture therapy (BNCT) with some positive res...
-
Chapter
Apoptosis of Tumor Cells in Response to Boron Neutron Capture Therapy
We examined the incidence of radiation-induced apoptosis in 9L gliosarcoma cells in response to gamma-ray irradiation (single doses of 1, 10, or 20Gy), neutron irradiation, and BNCT using BSH or boronated meta...
-
Chapter
Radiobiological Effects of Boronated Porphyrin (STA-BX909) Compared to BSH in Cultured Glioma Cell Line
Porphyrin is known as a tumor localizing agent that is clinically used in photo-dynamic therapy for cancers.1 Boronated porphyrins have also been developed2–7 and are now being investigated for possible clinical ...
-
Chapter
Cell Cycle Change of 9L Glioma Cell after in Vitro Boron Neutron Capture Therapy
Proliferating tumor cell progress through the phases of each cell cycle. Cell cycle change such as G2/M arrest is known to occur in tumor cells after γ ray radiation.1,2 However, cell cycle change of tumor cell a...
-
Chapter
The Advantage of Porphyrin for BNCT from the Point of View of Cell Cycle
The potential for using boronated porphyrins for BNCT have been reported by some groups.1–5 Our recent studies have also shown that porphyrin is one of the potential tumor targeting agents for BNCT.6,7 The tumor ...
-
Chapter
Boron-, Gadolinium-Porphyrin Derivatives for Neutron Capture Therapy
New porphyrin derivatives conjugated with boron(B) or gadolinium(Gd) were developed to use as compound for neutron capture therapy in order to obtain tumor selective accumulation of B or Gd. In neutron capture...
-
Chapter
Prediction of the Reversibility of the Brain Stem Dysfunction in Head Injury Patients: MRI and Auditory Brain Stem Response Study
16 cases of head injury patients were examined by magnetic resonance imaging (MRI) and auditory brain stem response (ABR) simultaneously in acute stage in order to investigate the possibility of the prediction...
