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Chapter
Tumor Cell Motility
Surgery, chemotherapy and radiotherapy are the current modalities of tumor management. However, in systemic disease, predicted patients’ cure can be achieved in but a few tumor diseases. Based on previous basi...
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Chapter
Effect of 12-HETE on the Expression of Autocrine Motility Factor-Receptor and Motility in Melanoma Cells
A 12-lipoxygenase metabolite of archidonic acid, 12-(S)-hydroxyglicosatetraenoic acid (12-(S)- HETE), which is synthesized by cancer cells was tested for its ability to affect the motility of K-1735 murine mel...
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Chapter and Conference Paper
Zellbewegung und Metastasierung: Über die Rolle des Rezeptors des autokrinen Motilitätsfaktors bei Tumorzellen
Die aktive Bewegung durch invadierende Tumorzellen wird als Voraussetzung für die Entstehung von sekundären Neoplasmen angesehen. Der Erfolg einer Metastasierung setzt die Invasion in das umgebende Normalgeweb...
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Chapter and Conference Paper
Cell Shape and the Metastatic Phenotype
The acquisition of the ability to metastasize is the ultimate and most deadly level of the tumorigenic progression. Metastatic cells are able to dissociate from the primary tumor, invade through the surroundin...
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Chapter
Pulmonary Localization of Intravenously Injected Liposomes
Clearance from the circulation and tissue distribution of liposomes of differing size, surface charge, and composition injected IV into BALB/c mice have been examined. Large (500–3,400 nm diameter) liposomes a...