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Chapter and Conference Paper
Physico-chemical Characterisation of the Processes Involved in Enamel Remineralisation by CPP-ACP
Casein phosphopeptides derived from tryptic digests of milk caseins spontaneously assemble with calcium and phosphate ions at high pH to form casein phosphopeptide-amorphous calcium phosphate complexes (CPP-AC...
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Chapter and Conference Paper
Protective Action of Reduced Water Against Alloxan-Induced Cytotoxicity in Pancreatic β-Cell
Previous studies showed that reduced water (RW) such as electrolyzed-reduced water (ERW) and natural reduced water (NRW) scavenge reactive oxygen species (ROS), protected DNA from oxidative damage, and stimula...
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Chapter and Conference Paper
Changes in the Relevant Test Parameters of 219 Diabetes Patients under the Influence of the So Called “Nordenau - Phenomenon” in the Prospective Observation Procedure
The study examined changes in the tests parameters of 219 diabetes patients (115 female, 104 male) under the influence of what is known as the “Nordenau-Phenomenon”, which attributes a healing effect to an old...
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Chapter and Conference Paper
Chemotaxis of Vascular Smooth Muscle Cells by Lysyl Oxidase
Purified bovine aorta lysyl oxidase conventionally oxidizes peptidyl lysine in elastin and collagen thus initiating the spontaneous formation of covalent crosslinkages between individual molecules of these fib...
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Chapter and Conference Paper
A Divergence in the Biosynthetic Pathway and a New Role for Vitamin B6
Studies on resistance of the fungus Cercospora nicotianae to singlet oxygen generating photosensitizers revealed new insights into the biological role of vitamin B6. Heterologous expression of a gene originally i...
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Chapter and Conference Paper
Cell and Antibody Engineering: New Tools for Antigen and Therapeutic Antibody Discovery
The inception of genetic engineering, the complete sequencing of human, animal and plant genomes, and the information revolution in the last quarter of the 20th century will forever change the way in which biolog...
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Chapter and Conference Paper
Analysis of Cell Death by Flow Cytometry
Apoptosis and necrosis denote two distinct modes of cell death. The distinction is based on differences in morphological, biochemical and molecular changes that occur within the dying cell (revie...
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Chapter and Conference Paper
GTPases: Key regulatory components of the endocytic pathway
GTP-binding proteins or GTPases are versatile cyclic molecular switches (Gilman, A.G. 1987 ; Bourne et al., 1990, 1992). In the past few years there has been an explosion of interest in unraveling the role of ...
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Chapter and Conference Paper
Oxidative stress and its relationship to carcinogen activation
Understanding the mechanism of activation of xenobiotics to biologically reactive derivatives as well as the resultant critical biological modifications provides a basis for both predicting toxicological risk ...
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Chapter and Conference Paper
Caps, Cors, Dehydrins, and Molecular Chaperones: Their Relationship with Low Temperature Responses in Spinach
When exposed to low non-freezing temperatures (0–10°C), the freezing tolerance of spinach increases in a time dependent fashion from an LT50 of -4°C to -14°C. Associated with the low temperature induction of f...
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Chapter and Conference Paper
Determinants of Outer Membrane Protein Sorting and Topology in Mitochondria
The mitochondrial outer and inner membrane each contains a distinct import machinery for translocating proteins into or across their respective lipid bilayers. These two translocators may function either indep...
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Chapter and Conference Paper
Osmotic Adjustment in Plant Cells Exposed to Drought and Temperature Stress: Can a Cause and Effect Hypothesis be Formulated and Tested?
The study of plant response to environmental stresses has developed rapidly during the past several decades. Attention has increasingly been devoted to the biochemical, biophysical, and physiological processes...
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Chapter and Conference Paper
Stable Expression of Human HSP70 Gene in Rodent Cells Confers Thermal Resistance
When exposed to a non lethal heat shock, a variety of organisms and cell lines acquire a transient resistance to one or more subsequent exposures at elevated temperatures (Gener and Schneider, 1975; Henle and ...
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Chapter and Conference Paper
Characteristics of Organic Anion Binding Proteins from Rat Liver Sinusoidal Plasma Membranes
Within the past decade it has become widely accepted that the entry into the hepatocyte of low molecular weight amphipathic organic compounds which are albumin-bound within the circulation is mediated by membr...
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Chapter and Conference Paper
The Role of Lipid-Protein Interactions in the Structure and Function of Photosynthetic Membranes
The mechanism and functional role of lipid-protein interactions in photosynthetic membranes has been examined. The efficacy of various acyl lipids in the restoration of energy and electron transfer between sol...
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Chapter and Conference Paper
Photolysis of the Photosensitizers Bithionol and Fentichlor
Antiseptic preparations containing bithionol (BT, 2,2′-thiobis(4,6-dichlorophenol)) and fentichlor (FT, 2,2′-thiobis(4-chlorophenol)) have been reported to cause contact photoallergy1,2, a delayed hypersensitivit...