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Prevalence and correlates of common mental disorders among participants of the Uganda Genome Resource: Opportunities for psychiatric genetics research
Genetics research has potential to alleviate the burden of mental disorders in low- and middle-income-countries through identification of new...
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Intracranial dissemination of Klebsiella pneumoniae originating from pulmonary infection: a case report
BackgroundMetastatic brain abscesses caused by Klebsiella pneumoniae are extremely rare but life-threatening conditions. To depict a unique case of...
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PIM1/NF-κB/CCL2 blockade enhances anti-PD-1 therapy response by modulating macrophage infiltration and polarization in tumor microenvironment of NSCLC
Elevated infiltration of tumor-associated macrophages (TAMs) drives tumor progression and correlates with poor prognosis for various tumor types. Our...
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Infertility as Trauma: Understanding the Lived Experience of Involuntary Childlessness
Infertility, to those who are affected by it, is much more than whether one manages (or not) to have a child: it can be a traumatizing experience....
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Identifying early symptoms associated with a diagnosis of childhood, adolescent and young adult cancers: a population-based nested case-control study
BackgroundChildhood, teenage and young adult (CTYA, 0–24 years) cancers are rare and diverse, making timely diagnosis challenging. We aim to explore...
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Religious Belief Among Women in Australia: Characteristics and Role in Influencing Children’s Health-Related Quality of Life and Lifestyle
Religiosity can be an important factor in women’s health-related behaviour, attitudes, and decision-making. Evidence however, regarding the...
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Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition
SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk...
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PET imaging of neuroinflammation: any credible alternatives to TSPO yet?
Over the last decades, the role of neuroinflammation in neuropsychiatric conditions has attracted an exponentially growing interest. A key driver for...
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Doing a double take: when transthoracic echocardiography fails for mitral valve annuloplasty ring endocarditis with Streptococcus pyogenes: a case report
BackgroundThis case highlights several complications of a late and rare presentation of culture-negative Streptococcus pyogenes endocarditis of a...
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Effectiveness of synthetic versus autologous bone grafts in foot and ankle surgery: a systematic review and meta-analysis
BackgroundAll orthopaedic procedures, comprising foot and ankle surgeries, seemed to show a positive trend, recently. Bone grafts are commonly...
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Social costs associated with fibromyalgia in Spain
BackgroundFibromyalgia is a chronic rheumatic disease of unknown aetiology, highly disabling and mainly affecting women. The aim of our work is to...
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Inhibitors of apolipoprotein C3, triglyceride levels, and risk of pancreatitis: a systematic review and meta-analysis
In recent years, novel apoC3 inhibitor therapies for the treatment of hypertriglyceridemia have been developed and assessed through phase II and III...
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Innovative approaches in discussions of diabetes among healthcare sector actors in Germany
The dramatic growth in the rate of diabetes prompts serious debates about awareness, early diagnosis, and care interventions. This Viewpoint aims to...
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Emerging biologic augmentation strategies for meniscal repair: a systematic review
BackgroundMeniscal repair should be the gold standard. However, the meniscus is poorly vascularized and even an excellent meniscus repair may not...
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Mindfulness in Orthopedic Rehabilitation: Can the Use of a Mindfulness Diary Positively Influence the Therapeutic Outcome of Orthopedic Rehabilitation?
ObjectivesMindfulness is a proven therapeutic practice for reducing anxiety, depression, and chronic pain, which are factors that influence the...
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Plastics and plastic-bound toxic metals in municipal solid waste compost from Sri Lanka
This study examined plastics and toxic metals in municipal solid waste compost from various regions in Sri Lanka. Plastics were extracted using...
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Impact and effect of imaging referral guidelines on patients and radiology services: a systematic review
ObjectivesThe objective of this systematic review was to offer a comprehensive overview and explore the associated outcomes from imaging referral...
