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Heterotrimeric collagen helix with high specificity of assembly results in a rapid rate of folding
The most abundant natural collagens form heterotrimeric triple helices. Synthetic mimics of collagen heterotrimers have been found to fold slowly,...
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Isolation and characterization of a two-coordinate phosphinidene oxide
Nitroso compounds, R–N=O, are common intermediates in organic synthesis, and are typically amenable to storage and manipulation at ambient...
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Outpatient reception via collaboration between nurses and a large language model: a randomized controlled trial
Reception is an essential process for patients seeking medical care and a critical component influencing the healthcare experience. However, current...
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The 2022 PSOGI International Consensus on HIPEC Regimens for Peritoneal Malignancies: Pseudomyxoma Peritonei
BackgroundThe combination of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) constitutes the established standard...
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Clinical features and underlying etiology of children with Lennox–Gastaut syndrome
ObjectiveLennox–Gastaut Syndrome (LGS) is characterized by the presence of multiple seizure types and encompasses a heterogenous group of etiologies....
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Panoramic tumor microenvironment in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is notorious for its resistance to various treatment modalities. The genetic heterogeneity of PDAC, coupled...
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Postoperative Adverse Events Following Neoadjuvant Therapy and Surgery for Borderline Resectable Pancreatic Cancer in a Phase 2 Clinical Trial (Alliance A021501)
BackgroundPostoperative adverse events (AEs) in patients with borderline resectable pancreatic ductal adenocarcinoma (BR-PC) treated with neoadjuvant...
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Cerium oxide nanofibers via electrospinning: a potential material to purge waterways of chemical pollutants and foodborne pathogens
Food is frequently contaminated by foodborne pathogens, predominantly bacteria and fungi but occasionally certain viruses as well as protozoa during...
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CD147 TagSNP is associated with the vulnerability to lung cancer in the Chinese population: a case–control study
BackgroundLung cancer, with its high morbidity and mortality, presents a major significant public health challenge. CD147, linked to cancer...
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A Translational Approach to Using Endocannabinoid Modulators for Targeting Opioid-Associated Memory
Purpose of ReviewIt is well established that learning and memory are central to substance dependence. Convincing basic and clinical documents...
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Circular walking is useful for assessing the risk of falls in early progressive supranuclear palsy
BackgroundProgressive supranuclear palsy (PSP) is characterized by early onset postural instability and frequent falls. Circular walking necessitates...
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DAP12 interacts with RER1 and is retained in the secretory pathway before assembly with TREM2
DNAX-activating protein of 12 kDa (DAP12) is a transmembrane adapter protein expressed in lymphoid and myeloid lineage cells. It interacts with...
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Therapeutic potential of Buddleja Polystachya Fresen (stem and leaves) extracts: antimicrobial and cytotoxic properties for ocular disease management
This study on Buddleja polystachya highlights its phytochemical composition, antimicrobial activity, and cytotoxic impacts. The study emphasizes the...
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Digital outcome measures are associated with brain atrophy in patients with multiple sclerosis
BackgroundDigital monitoring of people with multiple sclerosis (PwMS) using smartphone-based monitoring tools is a promising method to assess disease...