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Source-Sink Dynamics in a Two-Patch SI Epidemic Model with Life Stages and No Recovery from Infection
This study presents a comprehensive analysis of a two-patch, two-life stage SI model without recovery from infection, focusing on the dynamics of...
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Exploring the genetic basis of anthracnose resistance in Ethiopian sorghum through a genome-wide association study
BackgroundSorghum anthracnose is a major disease that hampers the productivity of the crop globally. The disease is caused by the hemibiotrophic...
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Design and Experiment of 2D Rectangular Solenoid Transmitting Coil for Novel Gastrointestinal Capsule Robot
A two-dimensional rectangular solenoid transmitting coil is proposed to address the problem that the three-dimensional receiving coil occupies...
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Silencing of ultradian rhythms and metabolic depression during spontaneous daily torpor in Djungarian hamsters
Ultradian rhythms of metabolism, body temperature and activity are attenuated or disappear completely during torpor in Djungarian hamsters, for all...
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Amla (Emblica officinalis)-Derived Bionanosilver (Ag NPs) for Excellent Antibacterial Activity
Despite the growing need for effective and environmentally friendly antimicrobial agents, the synthesis methods for such materials often involve...
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Investigating the effect of cerium oxide nanoparticle on beta-amyloid-induced memory loss
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the loss of nerve cells in the hippocampus region of the brain, leading to...
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Changes in the gut microbiota induced by an oral formulation of multiple peptides and plants contribute to its antihypertensive effects
The homeostasis of the gut microbiota is a crucial factor in regulating peripheral and central blood pressure. Formulating a food-derived mixture of...
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Differences in the seasonal development of perithecia by Neonectria ditissima on apple trees across Northern Europe
Ascospores discharged at rainfall and dispersed by wind can provide long-distance spread of the European canker fungus, Neonectria ditissima ....
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Pseudomonas aeruginosa PR23 isolated from oil contaminated soil tolerate and degrades mixture of polyaromatic hydrocarbons and express novel proteins
Pseudomonas aeruginosa PR23 isolated from the hydrocarbon contaminated soil can tolerate and degrade mixture of polyaromatic hydrocarbons (PAHs) at...
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Design, Characterization and Biopharmaceutical Applications of Novel Green Boron-Carbon Quantum Dots for Quantification of Apalutamide; Greenness Evaluations
The diagnosis of prostate cancer has been evolving in the current decade, with expected mortality rates of 499,000 death by the year 2030....
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Identification, validation and candidate gene analysis of major QTL for Supernumerary spikelets in wheat
BackgroundThe number of spikelets per spike is a key trait that affects the yield of bread wheat ( Triticum aestivum L.). Identification of the QTL...
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Purifying selection drove the adaptation of mitochondrial genes along with correlation of gene rearrangements and evolutionary rates in two subfamilies of Whitefly (Insecta: Hemiptera)
Insect mitochondrial genomes (mitogenomes) are usually represented by a conserved gene order. Whiteflies exhibit gene rearrangement in their...
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Hinesol attenuates DSS-induced ulcerative colitis through the suppression of Src-mediated NF-κB and chemokine signaling pathway
As a common inflammatory bowel disease, ulcerative colitis (UC) is featured with inflammation, oxidative damage, and the impairment of intestinal...
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Nucleoside and non-nucleoside reverse transcriptase inhibitor drugs (NRTIs and NNRTIs) are capable of binding Chandipura virus polymerase protein (L) and inhibit virus replication
Chandipura virus (CHPV) is an emerging pathogen of Indian subcontinent. It is a vector borne virus and belongs to Rhabdovirus family. In recent past...
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Rapid evolution of promoters from germline-specifically expressed genes including transposon silencing factors
BackgroundThe piRNA pathway in animal gonads functions as an ‘RNA-based immune system’, serving to silence transposable elements and prevent...
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Cas1 mediates the interference stage in a phage-encoded CRISPR–Cas system
Clustered regularly interspaced short palindromic repeats (CRISPR)–Cas systems are prokaryotic adaptive immune systems against invading phages and...
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Engineering miniature IscB nickase for robust base editing with broad targeting range
IscB has a similar domain organization to Cas9, but the small size of IscB is better suited for delivery by adeno-associated virus. To improve the...
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Complete substitution with modified nucleotides in self-amplifying RNA suppresses the interferon response and increases potency
The use of modified nucleotides to suppress the interferon response and maintain translation of self-amplifying RNA (saRNA), which has been achieved...