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Religious Belief Among Women in Australia: Characteristics and Role in Influencing Children’s Health-Related Quality of Life and Lifestyle
Religiosity can be an important factor in women’s health-related behaviour, attitudes, and decision-making. Evidence however, regarding the...
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Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition
SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk...
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PET imaging of neuroinflammation: any credible alternatives to TSPO yet?
Over the last decades, the role of neuroinflammation in neuropsychiatric conditions has attracted an exponentially growing interest. A key driver for...
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Doing a double take: when transthoracic echocardiography fails for mitral valve annuloplasty ring endocarditis with Streptococcus pyogenes: a case report
BackgroundThis case highlights several complications of a late and rare presentation of culture-negative Streptococcus pyogenes endocarditis of a...
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Effectiveness of synthetic versus autologous bone grafts in foot and ankle surgery: a systematic review and meta-analysis
BackgroundAll orthopaedic procedures, comprising foot and ankle surgeries, seemed to show a positive trend, recently. Bone grafts are commonly...
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Social costs associated with fibromyalgia in Spain
BackgroundFibromyalgia is a chronic rheumatic disease of unknown aetiology, highly disabling and mainly affecting women. The aim of our work is to...
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Diffusion-tensor magnetic resonance imaging as a non-invasive assessment of extracellular matrix remodeling in lumbar paravertebral muscles of rats with sarcopenia
BackgroundExtracellular matrix (ECM) remodeling in skeletal muscle is a significant factor in the development of sarcopenia. This study aims to...
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Inhibitors of apolipoprotein C3, triglyceride levels, and risk of pancreatitis: a systematic review and meta-analysis
In recent years, novel apoC3 inhibitor therapies for the treatment of hypertriglyceridemia have been developed and assessed through phase II and III...
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Emerging biologic augmentation strategies for meniscal repair: a systematic review
BackgroundMeniscal repair should be the gold standard. However, the meniscus is poorly vascularized and even an excellent meniscus repair may not...
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Stable Response and Sustained Improvement of Itch and Sleep Symptoms in Patients with Atopic Dermatitis Treated with Lebrikizumab over 52 Weeks
BackgroundLebrikizumab demonstrated significant improvement versus placebo for measures of skin clearance and patient-reported outcomes at weeks 16...
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A bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and promotes mania-like behavior
The single nucleotide polymorphism rs13166360, causing a substitution of valine (Val) 147 to leucine (Leu) in the adenylyl cyclase 2 (ADCY2), has...
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Multiple lung abscesses and cold agglutinin syndrome following coronavirus disease 2019: a case report
BackgroundCold agglutination syndrome is a subtype of autoimmune hemolytic anemia. The condition is referred to as “cold” because the antibodies...
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Statistical methods for discrimination of STR genotypes using high resolution melt curve data
Despite the improvements in forensic DNA quantification methods that allow for the early detection of low template/challenged DNA samples,...
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The effect of cesarean delivery on the neonatal gut microbiome in an under-resourced population in the Bronx, NY, USA
BackgroundNeonatal and early-life gut microbiome changes are associated with altered cardiometabolic and immune development. In this study, we...
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Rare tumours of the pancreas: monocentric study
PurposeThe biology of rare pancreatic tumours, which differs from that of ductal pancreatic cancer, requires increased attention. Although the...
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Magnitude of emergence agitation, its interventions and associated factors among paediatric surgical patients
BackgroundEmergence agitation is a transient confusional state of a child associated with consciousness from general anaesthesia, commonly occurs in...
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Hemorrhagic shock from gastric pseudoaneurysm post-percutaneous endoscopic gastrostomy: a case report
Percutaneous endoscopic gastrostomy (PEG) is widely used for long-term enteral nutrition in patients unable to maintain adequate oral intake. Despite...
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RET Inhibitors in RET Fusion-Positive Lung Cancers: Past, Present, and Future
While activating RET fusions are identified in various cancers, lung cancer represents the most common RET fusion-positive tumor. The clinical drug...
