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A deep learning-driven discovery of berberine derivatives as novel antibacterial against multidrug-resistant Helicobacter pylori
Helicobacter pylori ( H. pylori ) is currently recognized as the primary carcinogenic pathogen associated with gastric tumorigenesis, and its high...
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Chemotherapy’s effects on autophagy in the treatment of Hodgkin’s lymphoma: a sco** review
BackgroundClassical Hodgkin Lymphomas (HL) are a unique malignant growth with an excellent initial prognosis. However, 10–30% of patients will still...
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[18F]-D3FSP β-amyloid PET imaging in older adults and alzheimer’s disease
Purpose[ 18 F]-D3FSP is a new β-amyloid (Aβ) PET imaging tracer designed to decrease nonspecific signals in the brain by reducing the formation of the...
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The role of anti-citrullinated protein antibody in pathogenesis of RA
Rheumatoid arthritis (RA) is a common autoimmune rheumatic disease that causes chronic synovitis, bone erosion, and joint destruction. The...
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Prospective investigation of amino acid transport and PSMA-targeted positron emission tomography for metastatic lobular breast carcinoma
PurposeTo explore the feasibility of imaging amino-acid transport and PSMA molecular pathways in the detection of metastatic breast invasive lobular...
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Hypothyroidism after hemithyroidectomy: a systematic review and meta-analysis
BackgroundThe incidence of hypothyroidism following hemithyroidectomy and risk factors associated with its occurrence are not completely understood....
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Impact of DAA Treatment for HCV on Hepatocellular Carcinoma in a Predominately African American Population
PurposeThis study tested the hypothesis that our predominately AA medical center population would demonstrate a decline in HCV-driven HCC diagnosis...
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Comparison of synthesized and acquired high b-value diffusion-weighted MRI for detection of prostate cancer
BackgroundHigh b -value diffusion-weighted images (DWI) are used for detection of clinically significant prostate cancer (csPCa). This study...
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Spinal muscular atrophy caused by compound heterozygous SMN1 mutations: two cases and literature review
Spinal muscular atrophy (SMA) is a rare neuromuscular disease, which is characterized by the degeneration of motor neurons, leading to symmetrical...
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Efficacy and safety of tislelizumab plus bacillus-calmette guérin with or without chemotherapy as a bladder-sparing treatment for high-risk non-muscle-invasive bladder urothelial cancer: a real-world study
BackgroundDespite adequate transurethral resection of the bladder tumor (TURBT) followed by intravesical bacillus-calmette guérin (BCG), high-risk...
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The Effect of Obstructive Sleep Apnea on Cognition: A Focus on Decision-Making
Purpose of ReviewIn this review, we discuss the impact of Obstructive Sleep Apnea (OSA), a sleep-related breathing disorder characterized by...
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Multi-omics differences in the bone marrow between essential thrombocythemia and prefibrotic primary myelofibrosis
Essential thrombocythemia (ET) and prefibrotic primary myelofibrosis (pre-PMF) are Philadelphia chromosome-negative myeloproliferative neoplasms....
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Bupivacaine pleural effusion mimicking a hemothorax after a thoracoscopic microdiscectomy with epidural anesthesia
PurposePost-operative pain after video-assisted thoracoscopic surgery is often treated using thoracic epidural analgesics or thoracic paravertebral...
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Total-body dynamic PET/CT imaging reveals kinetic distribution of [13N]NH3 in normal organs
PurposeTo systematically investigate kinetic metrics and metabolic trap** of [ 13 N]NH 3 in organs.
MethodsEleven participants performed total-body [
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Cardiac safety of ribociclib evaluated with 24-hour rhythm Holter electrocardiogram
ObjectiveWe aimed to evaluate cardiac safety profile of ribociclib with 24-h rhythm Holter ECG.
Material and methodForty-two female metastatic...
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Exploring the integration of dentistry within a multidisciplinary palliative care team: does bedside dental care improve quality of life and symptom burden in inpatient palliative care patients?
BackgroundDespite the significant impact of oral problems on the quality of life of palliative care patients, comprehensive studies are lacking. This...