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Design, Characterization and Biopharmaceutical Applications of Novel Green Boron-Carbon Quantum Dots for Quantification of Apalutamide; Greenness Evaluations
The diagnosis of prostate cancer has been evolving in the current decade, with expected mortality rates of 499,000 death by the year 2030....
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Comparative Linkage of Novel Anti-Tumor Pd(II) Complex with Bio-Macromulecules: Fluorescence, UV-Vis, DFT, Molecular Docking and Molecular Dynamics Simulation Studies
A novel mononuclear palladium complex, [Pd(dach)(SSA)], where dach and SSA are diaminocyclohexane and sulfosalicylic acid ligands, respectively, has...
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Fabrication of Highly Sensitive and Selective Nitrite Colorimetric Sensor Based on the Enhanced Peroxidase Mimetic Activity of Using Acetic Acid Capped Zinc Oxide Nanosheets
Nitrite ions (NO 2 - ), as one of the leading type-A inorganic-anion, showing significant-effects in the aquatic environment and also to humans health....
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The 60-year evolution of lipid nanoparticles for nucleic acid delivery
Delivery of genetic information to the interior of target cells in vivo has been a major challenge facing gene therapies. This barrier is now being...
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In-Vitro Study of the Binding of Atorvastatin with Adenine using Multi-Spectroscopic Approaches
Atorvastatin—an oral lipid regulating drug is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase), which...
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Characterization of Prototype Gummy Formulations Provides Insight into Setting Quality Standards
Gummy formulations are considered suitable alternatives to traditional oral dosage forms like tablets and capsules due to their merits that include...
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Preparation and Evaluation of Berberine-Excipient Complexes in Enhancing the Dissolution Rate of Berberine Incorporated into Pellet Formulations
Berberine is used in the treatment of metabolic syndrome and its low solubility and very poor oral bioavailability of berberine was one of the...
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Sample Size Determination and Study Design Impact on Dose-Scale Pharmacodynamic Bioequivalence: a Case Study Using Orlistat
Dose-scale pharmacodynamic bioequivalence is recommended for evaluating the consistency of generic and innovator formulations of certain locally...
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Synthesis, Crystal Structure, Fluorescence and Theoretical Calculations of Three Zn(II)/Cd(II) Complexes with Bis-dentate N,N-Quinoline Schiff Base
Three d 10 metal complexes, ZnL(OAc) 2 ( 1 ), CdL(OAc) 2 ( 2 ) and [CdL 2 (NO 3 ) 2 ]·CH 3 CN ( 3 ) were synthesized using the ligand ( E )- N -(3-methoxy-4-methylphenyl)-...
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Eco-friendly Fluorescent Sensor for Sensitive and Selective Detection of Zn2+ and Fe3+ Ions: Applications in Human Hair Samples
A new eco-friendly sensor, 3-((6-((4-chlorobenzylidene)amino)pyridin-2-yl)imino)indolin-2-one ( CBAPI ) was synthesized and well characterized. The CBAPI ...
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Exploring the molecular binding mechanism of 6-fluoro, 4-hydroxy, 2- methyl quinoline with TiO2 nanoparticles: A spectroscopic, thermodynamic, and insights into the solvatochromic effect
This study investigates the interaction between titanium oxide nanoparticles (TiO 2 NPs) and the heterocyclic fluorophore...
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Investigation on the Influence of Solvents Environment on the Optoelectronic Properties of the Fluorescent Probe 1,3,4-Oxadiazole Analogues: A Combined Theoretical and Experimental Study
This study investigates the photophysical properties of a nitrobenzene-substituted 1,3,4-oxadiazole derivative (OX-NO) using both theoretical and...
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Biosynthesis, Structural, Spectroscopic, Photoluminescence, and Antifungal Activity of Ni-doped CeO2 Nanoparticles
Pedalium Murex leaf extract was used in this study to create Nickel-doped Cerium oxide (Ni-CeO 2 ) nanoparticles at 3 mol% and 5 mol% molar...
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Surface Passivation of Carbon Dots for Tunable Biological Performance
Recent investigations were shifted this trend toward exploring the biomedical applicability of CDs, relevant to chronic diseases. Herein, a...
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Recent Update on Nanocarrier(s) as the Targeted Therapy for Breast Cancer
Despite ongoing advances in cancer therapy, the results for the treatment of breast cancer are not satisfactory. The advent of nanotechnology...
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Nanosimilars: A Scientific or A Regulatory Debate?
The paper highlights the necessity for a robust regulatory framework for assessing nanomedicines and their off-patent counterparts, termed as...
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Quantum Computational and Spectroscopic Investigation of 3-aminosalicylic Acid
AbstractQuantum chemical calculations of 3-aminosalicylic acid (3ASA) (monomer and dimer forms) have been performed using DFT and TD-DFT theories...
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Nitroquinolone Fused Salicyl and Naphthyl Hydrazone Fluorescent Probes for the Detection of Fe3+and Pb2+ Ions
The application of quinolones stretches over a large umbrella of medicinal field as well as chemosensor due to the presence of privileged...
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Self-Sampling by Adolescents at Home: Assessment of the Feasibility to Successfully Collect Blood Microsamples by Inexperienced Individuals
Blood microsampling has increasingly attracted interest in the past decades as a more patient-centric sampling approach, offering the possibility to...
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The Influence of Various Freezing–thawing Methods of Skin on Drug Permeation and Skin Barrier Function
The selection of skin is crucial for the in vitro permeation test (IVPT). The purpose of this study was to investigate the influence of different...
