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  1. No Access

    Article

    Stress protein synthesis by crayfish CNS tissue in vitro

    Some crustacean axons remain functional for months after injury. This unusual property may require stress proteins synthesized by those neurons or provided to them by glial cells. To begin to explore this hypo...

    Julie M. Rochelle, Robert M. Grossfeld, Douglas L. Bunting in Neurochemical Research (1991)

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    Article

    Stress protein synthesis and accumulation after traumatic injury of crayfish CNS

    By several days after a crush injury of crayfish CNS, the wound site heals. Changes in protein synthesis and accumulation occur at the lesion site and nearby. During the first few hours, synthesis of 35, 70, 9...

    Zheng-yu Xue, Robert M. Grossfeld in Neurochemical Research (1993)

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    Article

    New carotenoids from the thermophilic green sulfur bacterium Chlorobium tepidum: 1′,2′-dihydro-γ-carotene, 1′,2′-dihydrochlorobactene, and OH-chlorobactene glucoside ester, and the carotenoid composition of different strains

    The complete carotenoid composition of the thermophilic green sulfur bacterium Chlorobium tepidum strain TNO was determined by spectroscopic methods. Major carotenoids were four kinds of carotenes: γ-carotene, c...

    S. Takaichi, Zheng-Yu Wang, Mitsuo Umetsu, Tsunenori Nozawa in Archives of Microbiology (1997)

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    Article

    A new method for protein domain recognition

    A fuzzy cluster method is presented to recognize protein domains. This algorithm can identify domains globally. A protein structure set was used to test the algorithm. Among 219 proteins, 66.7% yielded result...

    Zhen-Yu Xuan, Lun-Jiang Ling, Run-Sheng Chen in European Biophysics Journal (2000)

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    Article

    Changes of ATP and ADP in Cultured Astrocytes Under and After in Vitro Ischemia

    A very large body of evidence from in vivo studies has been accumulated on a link between the change of energy and cell survival/apoptosis. Using an in vitro ischemia model, we have previously shown that ische...

    Albert Cheung Hoi Yu, Anson Ming Fung Lau, Ada Wing Yu Fu in Neurochemical Research (2002)

  6. Article

    PGC-1α induces apoptosis in human epithelial ovarian cancer cells through a PPARγ-dependent pathway

    Peroxisome proliferator-activated receptor gamma (PPARγ) coactivator-1 alpha (PGC-1α) coactivates multiple transcription factors and regulates several metabolic processes. The current study investigated the ro...

    Yan Zhang, Yi Ba, Chang Liu, Guoxun Sun, Li Ding, Songyuan Gao, Jihui Hao in Cell Research (2007)

  7. Article

    Rig-I−/− mice develop colitis associated with downregulation of Gαi2

    RIG-I (retinoid acid-inducible gene-I), a putative RNA helicase with a cytoplasmic caspase-recruitment domain (CARD), was identified as a pattern-recognition receptor (PRR) that mediates antiviral immunity by ...

    Yi Wang, Hong-**n Zhang, Yue-** Sun, Zi-**ng Liu, Xue-Song Liu in Cell Research (2007)

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    Article

    Expression differentiation of CYC-like floral symmetry genes correlated with their protein sequence divergence in Chirita heterotricha (Gesneriaceae)

    CYCLOIDIEA (CYC) and its homologues have been studied intensively in the model organism Antirrhinum majus and related species regarding their function in controlling floral dorsoventral (adaxial–abaxial) asymmetr...

    Qiu Gao, Ju-Hong Tao, Dan Yan, Yin-Zheng Wang in Development Genes and Evolution (2008)

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    Article

    Comparative Proteomics Analysis of Cerebrospinal Fluid of Patients with Guillain–Barré Syndrome

    To better understand the pathophysiologic mechanisms underlying Guillain–Barré syndrome (GBS), Comparative proteomic analysis of cerebrospinal fluid (CSF) between patients with GBS (the experiment group) and c...

    Yin-Rong Yang, Shi-Lian Liu, Zhao-Yu Qin, Fu-Jun Liu in Cellular and Molecular Neurobiology (2008)

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    Article

    Microbial diversity in lake sediments detected by PCR-DGGE

    In this study, PCR-denaturing gradient gel electrophoresis (DGGE) was applied to analyze the microbial communities in lake sediments from Lake Xuanwu, Lake Mochou in Nan**g and Lake Taihu in Wuxi. Sediment sa...

    **nqing Zhao, Liuyan Yang, Can Chen, Lin **ao in Frontiers of Biology in China (2008)

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    Article

    Vesicular stomatitis virus matrix protein gene enhances the antitumor effects of radiation via induction of apoptosis

    Vesicular stomatitis virus (VSV) matrix (M) protein can directly induce apoptosis by inhibiting host gene expression when it is expressed in the absence of other viral components. Previously, we found that the...

    **ao-Bo Du, **-Yi Lang, Jian-Rong XU, You Lu, Yan-Jun Wen, Ju-Mei Zhao in Apoptosis (2008)

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    Article

    The Expression Pattern of Heterogeneous Nuclear Ribonucleoprotein R in Rat Retina

    The heterogeneous nuclear ribonucleoproteins (hnRNPs) play important roles in DNA repairing, cell signaling, telomere biogenesis, and in regulating gene expression at both transcriptional and translational lev...

    Zheng-Yu Peng, Jia Huang, Shu-Chen Lee, Yong-Liang Shi in Neurochemical Research (2009)

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    Article

    Zinc Deficiency Reduces Neurogenesis Accompanied by Neuronal Apoptosis Through Caspase-Dependent and -Independent Signaling Pathways

    Dietary zinc deficiency may affect zinc homeostasis in the brain and lead to reductions of neurogenesis and neuronal survival. However, the mechanisms responsible for the effects of zinc deficiency on hippocam...

    Hui-Ling Gao, Wei Zheng, Na **n, Zhi-Hong Chi, Zhen-Yu Wang in Neurotoxicity Research (2009)

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    Article

    Nitrogen fixation of epiphytic plants enwrap** trees in Ailao Mountain cloud forests, Yunnan, China

    Epiphytic plants play an important role in the nutrient cycle of forest ecosystems. There had been fewer studies in subtropical regions than in other climate zones. Prior research showed that the canopy epiphy...

    Bin Han, **aoming Zou, Jijun Kong, Liqing Sha, Hede Gong, Zhen Yu, Tong Cao in Protoplasma (2010)

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    Article

    Exposure to Pyrithiamine Increases β-Amyloid Accumulation, Tau Hyperphosphorylation, and Glycogen Synthase Kinase-3 Activity in the Brain

    Decreased thiamine-dependent enzyme activity and/or thiamine deficiency (TD) have been linked to Alzheimer’s disease (AD). In this study, we administered pyrithiamine, an anti-thiamine compound, to both APP/PS...

    **g Zhao, **ao**g Sun, Zhe Yu, **aoli Pan, Fenghua Gu, Jia Chen in Neurotoxicity Research (2011)

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    Article

    Excess Thyroid Hormone Inhibits Embryonic Neural Stem/Progenitor Cells Proliferation and Maintenance through STAT3 Signalling Pathway

    Hyperthyroidism is prevalent during pregnancy, but little is known about the effects of excess thyroid hormone on the development of embryonic neural stem/progenitor cells (NSCs), and the mechanisms underlying...

    Chunhai Chen, Zhou Zhou, Min Zhong, Maoquan Li, Xuesen Yang in Neurotoxicity Research (2011)

  17. Article

    The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation

    The MRE11/RAD50/NBS1 complex is the primary sensor rapidly recruited to DNA double-strand breaks (DSBs). MRE11 is known to be arginine methylated by PRMT1 within its glycine-arginine-rich (GAR) motif. In this ...

    Zhenbao Yu, Gillian Vogel, Yan Coulombe, Danielle Dubeau in Cell Research (2012)

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    Article

    Artificial Cold Wave-Induced Cerebral Infarction in Rats with Carotid Atherosclerosis

    To investigate the effects of cold on blood pressure, serum endothelin-1 content, serum nitric oxide content, and morbidity of cerebral infarction, as well as assess the therapeutic effect of nimodipine. A tot...

    Zhen-Yu Tang, Qiu-Yan Zhu, Li-Jun Xu, Li-Ying Deng in Journal of Molecular Neuroscience (2012)

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    Article

    Effect of Trehalose on PC12 Cells Overexpressing Wild-Type or A53T Mutant α-synuclein

    Accumulation of α-synuclein (α-Syn) is a common pathology for both familiar and sporadic Parkinson’s disease (PD), enhancing its clearance might be a promising strategy for treating PD. To assess the potential...

    Dan-Mei Lan, Feng-Tao Liu, Jian Zhao, Yan Chen, Jian-Jun Wu in Neurochemical Research (2012)

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    Article

    Cancer Microenvironment and Cancer Vaccine

    The cancer microenvironment is constituted of non-transformed host stromal cells such as endothelial cells, fibroblasts, various immune cells, and a complex extra-cellular matrix secreted by both the normal an...

    Zhen-Yu Ding, Xue-Lin Zou, Yu-Quan Wei in Cancer Microenvironment (2012)

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