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  1. Article

    Open Access

    Cancer cell-specific and pro-apoptotic SMAC peptide-doxorubicin conjugated prodrug encapsulated aposomes for synergistic cancer immunotherapy

    Immunogenic cell death (ICD) is a crucial approach to turn immunosuppressive tumor microenvironment (ITM) into immune-responsive milieu and improve the response rate of immune checkpoint blockade (ICB) therapy...

    **seong Kim, Man Kyu Shim, Yujeong Moon, Jeongrae Kim in Journal of Nanobiotechnology (2024)

  2. Article

    Open Access

    Preclinical development of carrier-free prodrug nanoparticles for enhanced antitumor therapeutic potential with less toxicity

    Nanomedicine has emerged as a promising strategy for cancer treatment. The most representative nanomedicine used in clinic is PEGylated liposomal doxorubicin DOXIL®, which is first FDA-approved nanomedicine. Howe...

    Man Kyu Shim, Suah Yang, Jooho Park, Jun Sik Yoon in Journal of Nanobiotechnology (2022)