297 Result(s)
within
Article
Yu-** Hung
Science, Humanities and Social Sciences, multidisciplinary
English
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Article
Open AccessOptimizing immunofluorescence with high-dynamic-range imaging to enhance PD-L1 expression evaluation for 3D pathology assessment from NSCLC tumor tissue
Assessing programmed death ligand 1 (PD-L1) expression through immunohistochemistry (IHC) is the golden standard in predicting immunotherapy response of non-small cell lung cancer (NSCLC). However, observation...
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Open AccessTransposase-assisted target-site integration for efficient plant genome engineering
The current technologies to place new DNA into specific locations in plant genomes are low frequency and error-prone, and this inefficiency hampers genome-editing approaches to develop improved crops1,2. Often co...
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Open AccessSex differences in the association of long-term exposure to heat stress on kidney function in a large Taiwanese population study
The incidence and prevalence of dialysis in Taiwan are high compared to other regions. Consequently, mitigating chronic kidney disease (CKD) and the worsening of kidney function have emerged as critical health...
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Open AccessThe risk of herpes zoster is positively associated with obesity, especially morbid obesity
This study aimed to investigate the association between obesity and herpes zoster (HZ) occurrence. This study used data covering 2 million people in Taiwan in 2000, which were obtained from the National Health...
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Open AccessStellae-123 gene expression signature improved risk stratification in Taiwanese acute myeloid leukemia patients
The European Leukemia Net recommendations provide valuable guidance in treatment decisions of patients with acute myeloid leukemia (AML). However, the genetic complexity and heterogeneity of AML are not fully ...
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Open AccessNew infundibulopelvic angle measurement method can predict stone-free rates following retrograde intrarenal surgery
To enhance the accuracy of predicting stone-free rates after retrograde intrarenal surgery, we devised a novel approach to assess the renal infundibulopelvic angle. We conducted a retrospective review of patie...
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Open AccessNeonatal jaundice is associated with increased risks of congenital anomalies of the kidney and urinary tract and concomitant urinary tract infection
The link between neonatal jaundice and urinary tract infection (UTI) remains debated, with congenital kidney and urinary tract anomalies (CAKUT) potentially playing a role. This population-based study aimed to...
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Open AccessAdvancing high-performance visible light communication with long-wavelength InGaN-based micro-LEDs
This study showcases a method for achieving high-performance yellow and red micro-LEDs through precise control of indium content within quantum wells. By employing a hybrid quantum well structure with our six ...
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Open AccessThree-dimensional ultrafast charge-density-wave dynamics in CuTe
Charge density waves (CDWs) involved with electronic and phononic subsystems simultaneously are a common quantum state in solid-state physics, especially in low-dimensional materials. However, CDW phase dynami...
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Open AccessProteomic analysis of serum extracellular vesicles from biliary tract infection patients to identify novel biomarkers
Biliary tract infection (BTI), a commonly occurring abdominal disease, despite being extensively studied for its initiation and underlying mechanisms, continues to pose a challenge in the quest for identifying...
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Open AccessInvestigating the effect of hypertension on vascular cognitive impairment by using the resting-state functional connectome
Hypertension (HTN) affects over 1.2 billion individuals worldwide and is defined as systolic blood pressure (BP) ≥ 140 mmHg and diastolic BP ≥ 90 mmHg. Hypertension is also considered a high risk factor for ce...
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Open AccessDiabetes mellitus modifies the association between chronic kidney disease–mineral and bone disorder biomarkers and aortic stiffness in peritoneal dialysis patients
This study aimed to investigate the relationship of four chronic kidney disease–mineral and bone disorder (CKD–MBD) biomarkers, including intact parathyroid hormone (PTH), fibroblast growth factor 23 (FGF23), ...
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Open AccessLong-term complications and outcomes of augmentation cystoplasty in children with neurogenic bladder
Augmentation cystoplasty (AC) is an effective surgical procedure for patients with neurogenic bladder whenever conservative treatments have failed. The present study aimed to determine the risks of metabolic c...
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Open AccessA Clinical Breathomics Dataset
This study entailed a comprehensive GC‒MS analysis conducted on 121 patient samples to generate a clinical breathomics dataset. Breath molecules, indicative of diverse conditions such as psychological and path...
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Open AccessA meta-analysis of sutureless scleral-fixated intraocular lens versus retropupillary iris claw intraocular lens for the management of aphakia
This study compared the visual outcomes and complications between sutureless scleral-fixated intraocular lens and iris claw intraocular lens implantation in aphakia without adequate capsule and/or zonule suppo...
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Open AccessDesign-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists
Although stapled α-helical peptides can address challenging targets, their advancement is impeded by poor understandings for making them cell permeable while avoiding off-target toxicities. By synthesizing >35...
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Open AccessWater can trigger nuclear reaction to produce energy and isotope gases
This paper reports the discovery that water can trigger a peculiar nuclear reaction and produce energy. Cavitation may induce unusual reactions through implosion of water vapor bubbles. Many of this research h...
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Open AccessThe association between alcohol, betel nut, and cigarette use with hepatitis C virus infection in Taiwan
Hepatitis C virus (HCV) infection may cause chronic liver disease, liver cirrhosis, and liver cancer. It has been reported to associate with habits including alcohol, betel nut and cigarette use. We aimed to i...
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Open AccessEffects of canagliflozin on cardiac remodeling and hemodynamic parameters in patients with type 2 diabetes mellitus
Sodium-glucose cotransporter type 2 (SGLT2) inhibitors have demonstrated to reduce cardiovascular risk in patients with type 2 diabetes mellitus (T2DM) in large trials independent of glycemic control. The mech...
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Open AccessHeart rhythm complexity analysis in patients with inferior ST-elevation myocardial infarction
Heart rhythm complexity (HRC), a subtype of heart rate variability (HRV), is an important tool to investigate cardiovascular disease. In this study, we aimed to analyze serial changes in HRV and HRC metrics in...
