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1,638 Result(s)
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Article
Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study
Selenium (Se) is an essential trace element for maintaining human health, for example, plays a crucial role in preventing aging-related diseases. However, most studies on the health effects of Se among the com...
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ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer’s disease mouse model
Olfactory dysfunction is increasingly recognized as an early indicator of Alzheimer’s disease (AD). Aberrations in GABAergic function and the excitatory/inhibitory (E/I) balance within the olfactory bulb (OB) ...
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Open AccessModulation of dlPFC function and decision-making capacity by repetitive transcranial magnetic stimulation in methamphetamine use disorder
This study explores the impact of repetitive transcranial magnetic stimulation (rTMS) on decision-making capabilities in individuals with methamphetamine use disorder (MUD), alongside potential underlying psyc...
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Open AccessMulti-omics differences in the bone marrow between essential thrombocythemia and prefibrotic primary myelofibrosis
Essential thrombocythemia (ET) and prefibrotic primary myelofibrosis (pre-PMF) are Philadelphia chromosome-negative myeloproliferative neoplasms. These conditions share overlap** clinical presentations; howe...
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Adsorption Performance of Chitosan and Glutaraldehyde Modified Biochars for Trivalent Antimony in Acidic Wastewater
Acidic wastewater from mining activities contains a large amount of Sb(III). Biochar can provide with an economical and efficacious method for removing of Sb(III). However, highly efficient removal was still c...
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Open AccessCultivation of novel Atribacterota from oil well provides new insight into their diversity, ecology, and evolution in anoxic, carbon-rich environments
The Atribacterota are widely distributed in the subsurface biosphere. Recently, the first Atribacterota isolate was described and the number of Atribacterota genome sequences retrieved from environmental samples ...
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Open AccessHuman cytomegalovirus infection impairs neural differentiation via repressing sterol regulatory element binding protein 2-mediated cholesterol biosynthesis
Congenital human cytomegalovirus (HCMV) infection is a major cause of abnormalities and disorders in the central nervous system (CNS) and/or the peripheral nervous system (PNS). However, the complete pathogene...
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Article
Correction to: Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
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Article
GSTO1 aggravates EGFR-TKIs resistance and tumor metastasis via deglutathionylation of NPM1 in lung adenocarcinoma
Despite significantly improved clinical outcomes in EGFR-mutant lung adenocarcinoma, all patients develop acquired resistance and malignancy on the treatment of EGFR tyrosine kinase inhibitors (EGFR-TKIs). Und...
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Article
Open AccessPyroptosis-related long-noncoding RNA signature predicting survival and immunotherapy efficacy in patients with lung squamous cell carcinoma
Pyroptosis-related long-noncoding RNAs (PRlncRNAs) play an important role in cancer progression. However, their role in lung squamous cell carcinoma (LUSC) is unclear. A risk model was constructed using the le...
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Open AccessOptimizing anterior urethral stricture assessment: leveraging AI-assisted three-dimensional sonourethrography in clinical practice
This investigation sought to validate the clinical precision and practical applicability of AI-enhanced three-dimensional sonographic imaging for the identification of anterior urethral stricture.
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Article
Combined Analysis of the Metabolome and Transcriptome Sheds New Light on the Mechanisms of Seed Maturation in Amorphophallus muelleri
Amorphophallus muelleri, a naturally occurring variant of the commercially valuable Amorphophallus species grown in Southeast Asia, stands out for its desirable traits: high konjac glucomannan (KGM) content, apom...
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Article
Open AccessEffectiveness of different intrusion modes of maxillary anterior teeth with mini-implants in clear aligner treatment: a three-dimensional finite element analysis
The intrusion of maxillary anterior teeth is often required and there are various intrusion modes with mini-implants in clear aligner treatment. The objective of this study was to evaluate the effectiveness of...
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Article
Risk factors and survival outcomes in children with early cardiotoxicity after allogeneic hematopoietic stem cell transplantation
Cardiotoxicity in children is a potentially fatal complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT); therefore, early identification of risk factors can improve patient prognosi...
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Open AccessSystem-level time computation and representation in the suprachiasmatic nucleus revealed by large-scale calcium imaging and machine learning
The suprachiasmatic nucleus (SCN) is the mammalian central circadian pacemaker with heterogeneous neurons acting in concert while each neuron harbors a self-sustained molecular clockwork. Nevertheless, how sys...
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Article
Deep learning for malignancy risk estimation of incidental sub-centimeter pulmonary nodules on CT images
To establish deep learning models for malignancy risk estimation of sub-centimeter pulmonary nodules incidentally detected by chest CT and managed in clinical settings.
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Open AccessPrevalence and related factors of nephrolithiasis among medical staff in Qingdao, China: a retrospective cross-sectional study
Certain occupations may predispose individuals to urolithiasis, a multi-factorial disease. The study aimed to evaluate the prevalence and related factors of nephrolithiasis in medical staff in Qingdao, China.
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Article
Recombination of variable and host range regions of glycoprotein gp85 in different avian leukosis virus subgroup K isolates
Given the high prevalence of avian leukosis virus subgroup K (ALV-K) in chickens in China, the positive rate of ALV-K in local chickens in Henan province was investigated, and the genetic region encoding the g...
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Article
Multi-level attention fusion network assisted by relative entropy alignment for multimodal speech emotion recognition
Multimodal speech emotion recognition can utilize features from different modalities simultaneously to improve the modeling capabilities in affective computing. However, the rough feature combining method may ...
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Open AccessHypertension and cardiac damage in pheochromocytoma and paraganglioma patients: a large-scale single-center cohort study
Hypertension (HT) is one of the most common manifestations in patients with catecholamine-secreting neuroendocrine tumors. Although the cardiovascular manifestations of these tumors have been described, there ...