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    The Lewy Body in Parkinson’s Disease and Related Neurodegenerative Disorders

    The histopathological hallmark of Parkinson’s disease (PD) is the presence of fibrillar aggregates referred to as Lewy bodies (LBs), in which α-synuclein is a major constituent. Pale bodies, the precursors of ...

    Koichi Wakabayashi, Kunikazu Tanji, Saori Odagiri, Yasuo Miki in Molecular Neurobiology (2013)

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    Neuropathology of Multiple System Atrophy, a Glioneuronal Degenerative Disease

    Multiple system atrophy (MSA) is a fatal disease characterized pathologically by the widespread occurrence of aggregated α-synuclein in the oligodendrocytes referred to as glial cytoplasmic inclusions (GCIs). ...

    Koichi Wakabayashi, Yasuo Miki, Kunikazu Tanji, Fumiaki Mori in The Cerebellum (2024)