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Neuropathology of Multiple System Atrophy, a Glioneuronal Degenerative Disease
Multiple system atrophy (MSA) is a fatal disease characterized pathologically by the widespread occurrence of aggregated α-synuclein in the oligodendrocytes referred to as glial cytoplasmic inclusions (GCIs). ...
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Article
The Lewy Body in Parkinson’s Disease and Related Neurodegenerative Disorders
The histopathological hallmark of Parkinson’s disease (PD) is the presence of fibrillar aggregates referred to as Lewy bodies (LBs), in which α-synuclein is a major constituent. Pale bodies, the precursors of ...