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Effect of Hypoxia-inducible Factor-1α Silencing on the Sensitivity of Human Brain Glioma Cells to Doxorubicin and Etoposide

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  1. Article

    Open Access

    Mesenchymal stem cells ameliorate hyperglycemia-induced endothelial injury through modulation of mitophagy

    Mitochondrial dysfunction and excessive mitochondrial reactive oxygen species (ROS) are fundamental contributors to endothelial injury in diabetic states. Mesenchymal stem cells (MSCs) have exhibited an extrao...

    Wuzheng Zhu, Yujia Yuan, Guangneng Liao, Lan Li, **g** Liu… in Cell Death & Disease (2018)

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  2. Article

    Open Access

    Peripheral infusion of human umbilical cord mesenchymal stem cells rescues acute liver failure lethality in monkeys

    Acute liver failure (ALF) is a complicated clinical syndrome associated with high mortality, with liver transplantation as the only treatment option. Treatment of mesenchymal stem cells has shown a potential t...

    Gang Guo, **ang Zhuang, Qing Xu, Zhenru Wu, Yongjie Zhu… in Stem Cell Research & Therapy (2019)

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  3. Article

    Open Access

    Intervention for early diabetic nephropathy by mesenchymal stem cells in a preclinical nonhuman primate model

    Diabetic nephropathy (DN) is one of the most severe chronic diabetic complications and the main cause of end-stage renal disease. Chronic inflammation plays a key role in the development of DN. However, few tr...

    **ngxing An, Guangneng Liao, Younan Chen, Ai Luo… in Stem Cell Research & Therapy (2019)

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  4. Article

    Open Access

    Macrophage-derived extracellular vesicles: diverse mediators of pathology and therapeutics in multiple diseases

    Macrophages (Mφ) are primary innate immune cells that exhibit diverse functions in response to different pathogens or stimuli, and they are extensively involved in the pathology of various diseases. Extracellu...

    Yizhuo Wang, Meng Zhao, Shuyun Liu, Jun Guo, Yanrong Lu… in Cell Death & Disease (2020)

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