Skip to main content

4 Result(s)

within English Remove this filter Medicine & Public Health Remove this filter Internal Medicine Remove this filter Y Lei Remove this filter Article Remove this filter

and

  1. No Access

    Article

    DACH1 attenuated PA-induced renal tubular injury through TLR4/MyD88/NF-κB and TGF-β/Smad signalling pathway

    Palmitic acid (PA), the major saturated fatty acid in the blood, often induces the initiation and progression of diabetic kidney disease (DKD). However, the underlying mechanism remains unclear. DACH1 is an im...

    J. Lin, B. Li, Q. Xu, Y. S. Liu, Y. L. Kang… in Journal of Endocrinological Investigation (2024)

  2. No Access

    Article

    EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1–TUFM protein complex

    Epidermal growth factor receptor (EGFR)-targeted therapy in head and neck squamous cell carcinoma (HNSCC) patients frequently results in tumor resistance to treatment. Autophagy is an emerging underlying resis...

    Y Lei, B A Kansy, J Li, L Cong, Y Liu, S Trivedi, H Wen, J P-Y Ting, H Ouyang… in Oncogene (2016)

  3. Article

    Open Access

    An ANCCA/PRO2000-miR-520a-E2F2 regulatory loop as a driving force for the development of hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) is one of the most common malignancies in Asia especially in China. We previously identified that ANCCA/PRO2000 as an important proliferation-associated protein predicted poor pr...

    J Huang, J Yang, Y Lei, H Gao, T Wei, L Luo, F Zhang, H Chen, Q Zeng, L Guo in Oncogenesis (2016)

    Download PDF (4615 KB) View Article

  4. No Access

    Article

    Inhibition of ANKRD1 sensitizes human ovarian cancer cells to endoplasmic reticulum stress-induced apoptosis

    High expression of Ankyrin Repeat Domain 1 (ANKRD1) in ovarian carcinoma is associated with poor survival, and in ovarian cancer cell lines is associated with platinum resistance. Importantly, decreasing ANKRD1 e...

    Y Lei, B R Henderson, C Emmanuel, P R Harnett, A deFazio in Oncogene (2015)