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  1. Article

    Open Access

    Effects of Local Administration of Iron Oxide Nanoparticles in the Prefrontal Cortex, Striatum, and Hippocampus of Rats

    Iron oxide nanoparticles (IONPs) are used for diverse medical approaches, although the potential health risks, for example adverse effects on brain functions, are not fully clarified. Several in vitro studies ...

    Ellen Irrsack, Julia Schuller, Charlotte Petters, Wiebke Willmann… in Neurotoxicity Research (2021)

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    Article

    How to Study the Uptake and Toxicity of Nanoparticles in Cultured Brain Cells: The Dos and Don’t Forgets

    Due to their exciting properties, engineered nanoparticles have obtained substantial attention over the last two decades. As many types of nanoparticles are already used for technical and biomedical applicatio...

    Wiebke Willmann, Ralf Dringen in Neurochemical Research (2019)

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    Article

    Monitoring of the Cytoskeleton-Dependent Intracellular Trafficking of Fluorescent Iron Oxide Nanoparticles by Nanoparticle Pulse-Chase Experiments in C6 Glioma Cells

    Iron oxide nanoparticles (IONPs) are used for various biomedical and therapeutic approaches. To investigate the uptake and the intracellular trafficking of IONPs in neural cells we have performed nanoparticle ...

    Wiebke Willmann, Ralf Dringen in Neurochemical Research (2018)