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Wen-**g **ng
Science, Humanities and Social Sciences, multidisciplinary
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Sensitivity of the Geophone
IN experimenting with a magneto-striction seismometer originally designed for geophysical prospecting, some characteristics of the instrument were observed to be of interest. The geophone, when combined with a...
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Gravitational Data from the Nan Shan Range
STUDYING the gravitational data obtained in the front of the Nan Shan Range, China, interesting facts pertaining to the crustal structure of the earth are revealed. The gravimetric survey was not primarily car...
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Inhibition of Acetylcholinesterase by Reserpine in Suspension
IN the routine examination of compounds as possible inhibitors of enzymatic reactions, it appears to be fairly common practice to ignore that part of the added compound which remains in suspension in the react...
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Some Palæomagnetic Investigations on Chinese Rocks
PREVIOUS palæomagnetic investigations1 on European and North American rocks agree in suggesting that those areas were in such a position that the pole appeared to lie on or near the Chinese mainland from Upper Pa...
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Toxicity of Boron to Rice
IN the course of a study on the chemical retardation of soil reduction as a remedy for physiological disorders of the rice plant, we observed that despite this retardation by calcium nitrate and manganese diox...
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Are opioid peptides co-transmitters in noradrenergic vesicles of sympathetic nerves?
Biogenic amines and peptide hormones co-exist in paraneurones1 or amine precursor uptake and decarboxylation (APUD) cells2. Opioid peptide immunohistofluorescence occurs in the gland cells and nerve endings of th...
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Pseudogenes as a paradigm of neutral evolution
On the neutral mutation hypothesis1–3, the rate of nucleotide substitution is expected to be higher for functionally less important genes or parts of genes than for functionally more important genes, as the latte...
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Positive selection causes purifying selection (reply)
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Dynamic uplift of the Himalaya
It has become widely accepted that the Himalaya is the product of collision between the Indian landmass and the Eurasian continent. Holmes1 conjectured that the Indian Shield was carried northwards by sub-lithosp...
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Rearranged c-mos locus in a MOPC 21 murine myeloma cell line and its persistence in hybridomas
Studies of a number of normal and carcinogen-transformed murine cell lines, and a variety of murine tissues, have indicated that, in contrast to several other cellular oncogenes, the oncogene c-mos gene is usuall...
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High heat flow in southern Tibet
Heat flow measurements have been attempted in two freshwater lakes at altitudes of 4.5 and 5.0 km, south of the Yarlung–Zangbo suture zone in southern Tibet. Probe penetration in the lake sediments was deep en...
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Expression and amplification of the N-myc gene in primary retinoblastoma
Retinoblastoma, the most common intraocular tumour of childhood, probably arises from embryonal cells and occurs in hereditary and non-hereditary forms1. Recent evidence suggests that this retinoblastoma (Rb) sus...
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Preliminary Phanerozoic polar wander paths for the North and South China blocks
Polar wander paths for the North and South China blocks suggest that (1) both were parts of Gondwana in the Palaeozoic, (2) the North China block accreted to Siberia in the late Permian and (3) the South China...
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Local degradation of fibronectin at sites of expression of the transforming gene product pp60src
Local degradation of extracellular fibronectin, a major extracellular adhesive protein, is believed to play an important part in the migration of cells through the extracellular matrix during tumour invasion, ...
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Sequence, structure, receptor-binding domains and internal repeats of human apolipoprotein B-100
Apolipoprotein (apo) B-100, the major protein component in low density lipoprotein (LDL), is the ligand that binds to the LDL receptor1. It is important in the metabolism of LDL and elevated plasma levels of LDL-...
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The molecular clock runs more slowly in man than in apes and monkeys
The molecular clock hypothesis1 postulates that the rate of molecular evolution is approximately constant over time. Although this hypothesis has been highly controversial in the past, it is now widely accepted2–...
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The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity
The human gene (RB) that determines susceptibility to hereditary retinoblastoma has been identified recently by molecular genetic techniques1,2,14. Previous results indicate that complete inactiva-tion of the RB
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Receptor-directed focusing of lymphokine release by helper T cells
The interaction between helper T cells and B cells, leading to the production of antibody to thymus-dependent antigens, was the first cell interaction clearly defined in the immune system1–3; it remains both par...
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Understanding the origins of AIDS viruses
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Mutation rates differ among regions of the mammalian genome
In the traditional view of molecular evolution, the rate of point mutation is uniform over the genome of an organism and variation in the rate of nucleotide substitution among DNA regions reflects differential...
