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  1. Article

    Open Access

    The artificial neural network approach based on uniform design to optimize the fed-batch fermentation condition: application to the production of iturin A

    Iturin A is a potential lipopeptide antibiotic produced by Bacillus subtilis. Optimization of iturin A yield by adding various concentrations of asparagine (Asn), glutamic acid (Glu) and proline (Pro) during the ...

    Wen**g Peng, Juan Zhong, Jie Yang, Yanli Ren, Tan Xu in Microbial Cell Factories (2014)

  2. Article

    Open Access

    Establishment and application of a CRISPR–Cas12a assisted genome-editing system in Zymomonas mobilis

    Efficient and convenient genome-editing toolkits can expedite genomic research and strain improvement for desirable phenotypes. Zymomonas mobilis is a highly efficient ethanol-producing bacterium with a small gen...

    Wei Shen, Jun Zhang, Binan Geng, Mengyue Qiu, Mimi Hu in Microbial Cell Factories (2019)

  3. Article

    Open Access

    Development of a counterselectable system for rapid and efficient CRISPR-based genome engineering in Zymomonas mobilis

    Zymomonas mobilis is an important industrial bacterium ideal for biorefinery and synthetic biology studies. High-throughput CRISPR-based genome editing technologies have been developed to enable targeted engineer...

    Yanli Zheng, Hongmei Fu, Jue Chen, Jie Li, Yuejie Bian, ** Hu in Microbial Cell Factories (2023)