13 Result(s)

Article

Low-dose tacrolimus (FK506)-based immunosuppressive protocol in living donor renal transplantation

In order to avoid the side effects of tacrolimus (FK506), a low-dose FK506-based regimen was started from 1 June 1991. The dose was adjusted to maintain the FK506 whole blood trough level at 15–20 ng/ml for 7...

Y. Kokado, S. Takahara, M. Kyo, N. Ichimaru, W. **g-Ding… in Transplant International (1998)

Article

Abstracts

Hans-Jürgen Kaatsch, K. Püschel, A. Heinemann, Jakob Klaas, Hildegard Graß… in Rechtsmedizin (2000)

Article

A Rac1/PAK1 cascade controls β-catenin activation in colon cancer cells

P21-activated kinase 1 (PAK1) is associated with colon cancer progression and metastasis, whereas the molecular mechanism remains elusive. Here, we show that downregulation of PAK1 in colon cancer cells reduce...

G Zhu, Y Wang, B Huang, J Liang, Y Ding, A Xu, W Wu in Oncogene (2012)

Article

Nuclear loss of protein arginine N-methyltransferase 2 in breast carcinoma is associated with tumor grade and overexpression of cyclin D1 protein

Human protein arginine N-methyltransferase 2 (PRMT2, HRMT1L1) is a protein that belongs to the arginine methyltransferase family, and it has diverse roles in transcriptional regulation through different mechanism...

J Zhong, R-X Cao, J-H Liu, Y-B Liu, J Wang, L-P Liu, Y-J Chen, J Yang… in Oncogene (2014)

Article

Successful early unmanipulated haploidentical transplantation with reduced-intensity conditioning for primary graft failure after cord blood transplantation in hematologic malignancy patients

Primary graft failure (pGF) is a frequent complication following cord blood transplantation (CBT). For those patients who will not experience autologous recovery, salvage transplantation should be performed as...

B L Tang, X Y Zhu, C C Zheng, H L Liu, L Q Geng, X B Wang… in Bone Marrow Transplantation (2015)

Article

H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo

Histone H3 K27M mutation is the defining molecular feature of the devastating pediatric brain tumor, diffuse intrinsic pontine glioma (DIPG). The prevalence of histone H3 K27M mutations indicates a critical ro...

André B. Silveira, Lawryn H. Kasper, Yi** Fan, Hongjian **… in Acta Neuropathologica (2019)

Article

Extracellular vesicles derived from bone marrow mesenchymal stem cells alleviate neuroinflammation after diabetic intracerebral hemorrhage via the miR-183-5p/PDCD4/NLRP3 pathway

Intracerebral hemorrhage (ICH) induced by diabetes results in further brain injury and nerve cell death. Bone marrow mesenchymal stem cell (BMSC) transplantation contributes to attenuating neurological deficit...

H. Ding, Y. Jia, H. Lv, W. Chang, F. Liu… in Journal of Endocrinological Investigation (2021)

Article

Dichotomous regulation of striatal plasticity by dynorphin

Modulation of corticostriatal plasticity alters the information flow throughout basal ganglia circuits and represents a fundamental mechanism for motor learning, action selection, and reward. Synaptic plastici...

Renzhi Yang, Rupa R. Lalchandani Tuan, Fuu-Jiun Hwang… in Molecular Psychiatry (2023)