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Article
Open AccessUtility of a virtual small group cognitive behaviour program for autistic children during the pandemic: evidence from a community-based implementation study
Autistic children often experience socioemotional difficulties relating to emotion regulation and mental health problems. Supports for autistic children involve the use of adapted interventions that target emo...
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Article
Open AccessImpact of Bacteria Types on the Clinical Outcomes of Spontaneous Bacterial Peritonitis
Cirrhotic patients presenting with spontaneous bacterial peritonitis (SBP) have elevated risk of short-term mortality. While high Model for End-Stage Liver Disease-Sodium score (MELD-Na) and ascites culture yi...
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Article
Patient perspectives on window of opportunity clinical trials in early-stage breast cancer
Window of opportunity trials (WOT) are increasingly common in oncology research. In WOT participants receive a drug between diagnosis and anti-cancer treatment, usually for the purpose of investigating that dr...
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Article
Open AccessBiocompatibility and feasibility of VisiPlate, a novel ultrathin, multichannel glaucoma drainage device
Glaucoma is the leading cause of blindness worldwide. Glaucoma drainage devices and minimally invasive glaucoma surgeries (MIGS) often present with tradeoffs in safety and durability of efficacy. Using a rabbi...
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Article
Open AccessRetina tissue validation of optical coherence tomography determined outer nuclear layer loss in FTLD-tau
Alzheimer’s disease (AD) is associated with inner retina (nerve fiber and ganglion cell layers) thinning. In contrast, we have seen outer retina thinning driven by photoreceptor outer nuclear layer (ONL) thinn...
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Article
An investigation of “We” agency in co-operative joint actions
Sense of agency refers to the sense that I am controlling an action or outcome, and is associated with a perceived compression of the temporal interval between these events known as intentional binding (IB). T...
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Article
The WISDOM study: a new approach to screening can and should be tested
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Open AccessPharmacists reinventing their roles to effectively respond to COVID-19: a global report from the international pharmacists for anticoagulation care taskforce (iPACT)
SARS-CoV2 is dramatically impacting the global population. Worldwide, pharmacists are changing their roles and being increasingly recognized for their role as essential service providers. This commentary provi...
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Awareness campaigns of atrial fibrillation as an opportunity for early detection by pharmacists: an international cross-sectional study
Atrial fibrillation (AF) accounts for up to one third of strokes, one of the lead mortality causes worldwide. The European Society of Cardiology guidelines recommend opportunistic screening as a means to incre...
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Article
Multiscale reverse engineering of the human ocular surface
Here we present a miniaturized analog of a blinking human eye to reverse engineer the complexity of the interface between the ocular system and the external environment. Our model comprises human cells and pro...
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Article
Open AccessDeep learning networks find unique mammographic differences in previous negative mammograms between interval and screen-detected cancers: a case-case study
To determine if mammographic features from deep learning networks can be applied in breast cancer to identify groups at interval invasive cancer risk due to masking beyond using traditional breast density meas...
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Article
Open AccessVenous Endothelial Marker COUP-TFII Regulates the Distinct Pathologic Potentials of Adult Arteries and Veins
Arteries and veins have very different susceptibility to certain vascular diseases such as atherosclerosis and vascular calcification. The molecular mechanisms of these differences are not fully understood. In...
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Article
Brief Report: Infants Develo** with ASD Show a Unique Developmental Pattern of Facial Feature Scanning
Infants are interested in eyes, but look preferentially at mouths toward the end of the first year, when word learning begins. Language delays are characteristic of children develo** with autism spectrum dis...
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Open AccessThe emergency to home project: impact of an emergency department care coordinator on hospital admission and emergency department utilization among seniors
Seniors comprise 14% to 21% of all emergency department (ED) visits, yet are disproportionately larger users of ED and inpatient resources. ED care coordinators (EDCCs) target seniors at risk for functional de...
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Article
Thermal environment shapes cuticle melanism and melanin-based immunity in the ground cricket Allonemobius socius
The thermal melanin hypothesis posits that ectothermic individuals of larger size or from colder environments exhibit darker cuticles due to melanin’s efficacy in absorbing solar radiation. However, melanin is...
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Article
Open AccessThe BioLexicon: a large-scale terminological resource for biomedical text mining
Due to the rapidly expanding body of biomedical literature, biologists require increasingly sophisticated and efficient systems to help them to search for relevant information. Such systems should account for ...
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Article
IL-17E, a proinflammatory cytokine, has antitumor efficacy against several tumor types in vivo
Interleukin-17E (IL-17E) belongs to a novel family of cytokines that possess significant homology to IL-17. IL-17E has potent inflammatory effects in vitro and in vivo. Overexpression of IL-17E in mice results...
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Article
Open AccessRisk factors for human infection with West Nile Virus in Connecticut: a multi-year analysis
The optimal method for early prediction of human West Nile virus (WNV) infection risk remains controversial. We analyzed the predictive utility of risk factor data for human WNV over a six-year period in Conne...
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Article
Virulizin® induces production of IL-17E to enhance antitumor activity by recruitment of eosinophils into tumors
Virulizin® has demonstrated strong antitumor efficacy in a variety of human tumor xenograft models including melanoma, pancreatic cancer, breast cancer, ovarian cancer and prostate cancer. Our previous studies ha...
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Open AccessAssessment of disease named entity recognition on a corpus of annotated sentences
In recent years, the recognition of semantic types from the biomedical scientific literature has been focused on named entities like protein and gene names (PGNs) and gene ontology terms (GO terms). Other sema...
