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  1. No Access

    Article

    Effect of erythropoiesis-stimulating agents on breast cancer patients: a meta-analysis

    Erythropoiesis-stimulating agents (ESAs) have been reported to increase the risk of death in cancer patients. In this study, we selected breast cancer, which is currently the most prevalent cancer worldwide, ...

    Tong Wu, Zhenhua Tong, Tianshu Ren, Danni **e… in Clinical and Experimental Medicine (2023)

  2. No Access

    Article

    FAK inhibitor PF-562271 inhibits the migration and proliferation of high-grade serous ovarian cancer cells through FAK and FAK mediated cell cycle arrest

    Focal adhesion kinase (FAK) is a promising therapeutic target for various cancers and its inhibitor development is in full swing. PF-562271 is a classic FAK inhibitor that has shown promising preclinical data ...

    Qionghui Pan, Qingyu Wang, Tianshu Zhao, **nyu Zhao, Yixin Liang… in Medical Oncology (2023)

  3. No Access

    Article

    Intra-tumor metabolic heterogeneity of gastric cancer on 18F-FDG PETCT indicates patient survival outcomes

    The present study aimed to investigate the prognostic value of intra-tumor metabolic heterogeneity on 2-[18F] Fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) for patie...

    Guobing Liu, Hongyan Yin, ** Cheng, Yan Wang, Yan Hu… in Clinical and Experimental Medicine (2021)

  4. No Access

    Article

    A prospective observational study on the optimal maintenance strategy in HER2-positive advanced gastric cancer treated with trastuzumab-based therapy

    Trastuzumab plus chemotherapy is an effective therapy in HER2 positive advanced gastric cancer (AGC). However, the optimal maintenance treatment in patients benefited from the first line therapy remains unclear.

    Qian Li, Minzhi Lv, Huiqin Jiang, Yan Wang… in Journal of Cancer Research and Clinical On… (2020)

  5. No Access

    Article

    K-Ras mutation detection in liquid biopsy and tumor tissue as prognostic biomarker in patients with pancreatic cancer: a systematic review with meta-analysis

    K-Ras gene mutations have been found in most pancreatic cancers; however, conflicting data on the prognostic value of K-Ras mutations in pancreatic cancer have been published. We conducted a meta-analysis to a...

    Tao Li, Yuanting Zheng, Hong Sun, Rongyuan Zhuang, **g Liu… in Medical Oncology (2016)

  6. No Access

    Article

    Low-dosed docetaxel showed equivalent efficacy but improved tolerability compared with oxaliplatin in the S-1-based first-line chemotherapy regimen for metastatic or recurrent gastric adenocarcinoma

    Platinum–fluoropyrimidine combinations are the preferred first-line options for advanced gastric cancer (AGC) in East Asia. On the other hand, docetaxel-containing regimens without platinum have demonstrated p...

    Mengzhou Guo, Yiyi Yu, Yan Wang, Yuehong Cui, Qian Li, Yi Feng, Wei Li… in Medical Oncology (2015)

  7. Article

    Open Access

    Analysis of UGT1A1*28 genotype and SN-38 pharmacokinetics for irinotecan-based chemotherapy in patients with advanced colorectal cancer: results from a multicenter, retrospective study in Shanghai

    The UGT1A1*28 polymorphism, although closely linked with CPT-11-related adverse effects, cannot be used alone to guide individualized treatment decisions. However, CPT-11 dosage can be adjusted according to m...

    Xun Cai, Weiguo Cao, Honghua Ding… in Journal of Cancer Research and Clinical On… (2013)

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