15 Result(s)
within
Science, Humanities and Social Sciences, multidisciplinary
Tianhe **ao
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Open AccessGenetic association of PROC variants with pulmonary embolism in Northern Chinese Han population
To evaluate SNPs (single nucleotide polymorphism) in PROC (protein C gene) associated with pulmonary embolism (PE) susceptibility in North Chinese Han population. A case-control study design was used, and patien...
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Open AccessReversible Brain Abnormalities in People Without Signs of Mountain Sickness During High-Altitude Exposure
A large proportion of lowlanders ascending to high-altitude (HA) show no signs of mountain sickness. Whether their brains have indeed suffered from HA environment and the persistent sequelae after return to lo...
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Open AccessExperimental and mechanistic research on methane adsorption in anthracite modified by electrochemical treatment using selected electrode materials
The strong adsorption capacity of methane in anthracite can seriously affect the methane extraction. Electrochemical treatment is an effective way to weaken the capacity of methane adsorption in coal. Iron, co...
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Open AccessEffective combinatorial immunotherapy for penile squamous cell carcinoma
Penile squamous cell carcinoma (PSCC) accounts for over 95% of penile malignancies and causes significant mortality and morbidity in develo** countries. Molecular mechanisms and therapies of PSCC are underst...
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Open AccessDifferent computed tomography patterns of Coronavirus Disease 2019 (COVID-19) between survivors and non-survivors
This study aimed to compare the chest computed tomography (CT) findings between survivors and non-survivors with Coronavirus Disease 2019 (COVID-19). Between 12 January 2020 and 20 February 2020, the records o...
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Open AccessUQCRH downregulation promotes Warburg effect in renal cell carcinoma cells
Ubiquinol-cytochrome c reductase hinge protein (UQCRH) is the hinge protein for the multi-subunit complex III of the mitochondrial electron transport chain and is involved in the electron transfer reaction bet...
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Open AccessCRISPR screening of porcine sgRNA library identifies host factors associated with Japanese encephalitis virus replication
Japanese encephalitis virus (JEV) is a mosquito-borne zoonotic flavivirus that causes encephalitis and reproductive disorders in mammalian species. However, the host factors critical for its entry, replication...
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Open AccessAccuracy of hand localization is subject-specific and improved without performance feedback
Accumulating evidence indicates that the spatial error of human's hand localization appears subject-specific. However, whether the idiosyncratic pattern persists across time with good within-subject consistenc...
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Open AccessA novel deep learning-based quantification of serial chest computed tomography in Coronavirus Disease 2019 (COVID-19)
This study aims to explore and compare a novel deep learning-based quantification with the conventional semi-quantitative computed tomography (CT) scoring for the serial chest CT scans of COVID-19. 95 patients...
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Open AccessOmicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies
The SARS-CoV-2 B.1.1.529 (Omicron) variant contains 15 mutations of the receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies requires immediate investigation. Here we use high...
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Open AccessHigh drug-loaded microspheres enabled by controlled in-droplet precipitation promote functional recovery after spinal cord injury
Drug delivery systems with high content of drug can minimize excipients administration, reduce side effects, improve therapeutic efficacy and/or promote patient compliance. However, engineering such systems is...
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Open AccessBound states at partial dislocation defects in multipole higher-order topological insulators
The bulk-boundary correspondence, which links a bulk topological property of a material to the existence of robust boundary states, is a hallmark of topological insulators. However, in crystalline topological ...
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Open AccessBA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages BA.2.12.1, BA.4 and BA.5 exhibit higher transmissibility than the BA.2 lineage1. The receptor binding and immune-evasion capability...
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Open AccessImprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution
Continuous evolution of Omicron has led to a rapid and simultaneous emergence of numerous variants that display growth advantages over BA.5 (ref. 1). Despite their divergent evolutionary courses, mutations on the...
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Open AccessRepeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting
The continuing emergence of SARS-CoV-2 variants highlights the need to update COVID-19 vaccine compositions. However, immune imprinting induced by vaccination based on the ancestral (hereafter referred to as W...
