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Open AccessA user study for evaluation of formal verification results and their explanation at Bosch
Ensuring safety for any sophisticated system is getting more complex due to the rising number of features and functionalities. This calls for formal methods to entrust confidence in such systems. Nevertheless,...
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Article
Open AccessThe impact of prior endoscopic or surgical therapy on open Zenker’s diverticulum surgery: analysis on a large single center cohort
Endoscopic treatment of Zenker’s diverticulum is an attractive minimally invasive alternative compared to the classic open approach. However, increased recurrence rate were reported. In case of relapse, endosc...
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Article
Open AccessEx situ arterial reconstruction prior normothermic machine perfusion of liver grafts
Atypical variants of the hepatic artery are common and pose a technical challenge for normothermic machine perfusion (NMP). The transplant surgeon has three options when confronted with hepatic arterial variat...
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Article
Open AccessSerum albumin at resection predicts in-hospital death, while serum lactate and aPTT on the first postoperative day anticipate anastomotic leakage after Ivor-Lewis-esophagectomy
Anastomotic leakage (AL) is a major complication after esophagectomy, potentiating morbidity and mortality. There are several patient risk factors associated with AL, but high-fidelity postoperative predictors...
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Article
Humoral immune response after COVID-19 infection or BNT162b2 vaccine among older adults: evolution over time and protective thresholds
The objectives of this study were to assess the dynamics of the SARS-CoV-2 anti-RBD-IgG response over time among older people after COVID-19 infection or vaccination and its comparison with indicative levels o...
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Therapeutic prevention of COVID-19 in elderly: a case–control study
COVID-19 is a particularly aggressive disease for the elderly as 86% of deaths related to COVID-19 occur in people over 65 years of age. Despite the urgent need for a preventive treatment, there are currently...
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Article
Open AccessEffective operating room (OR) utilization by performing low-complex surgical procedures during the 2020 corona pandemic
The SARS-CoV-2 pandemic has almost stopped all elective surgical treatment throughout the world. As operating room (OR) capacities are reduced everywhere to ensure availability of intensive care capacities, es...
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Article
Open AccessComplete mesocolic excision in minimally invasive surgery of colonic cancer: do we need the robot?
Robotic surgery offers favorable prerequisites for complex minimally invasive surgeries which are delivered by higher degrees of freedom, improved instrument stability, and a perfect visualization in 3D which ...
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Article
Open AccessEffect of 9 weeks continuous vs. interval aerobic training on plasma BDNF levels, aerobic fitness, cognitive capacity and quality of life among seniors with mild to moderate Alzheimer’s disease: a randomized controlled trial
Evidence suggests that aerobic-type training confers physical benefits and appears to contribute positively to brain health. This study aims to compare the effect of 9-weeks continuous (CAT) to interval aerobi...
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Article
Potential Statin Overuse in Older Patients: A Retrospective Cross-Sectional Study Using French Health Insurance Databases
Although compelling evidence exists supporting statins (HMG-CoA reductase inhibitors) for secondary prevention in older patients with clinical atherosclerotic diseases, the same cannot be said for primary prev...
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Article
Mortality and postoperative complications after different types of surgical reconstruction following pancreaticoduodenectomy—a systematic review with meta-analysis
Pancreaticoduodenectomy/PD is a technically demanding pancreatic resection. Options of surgical reconstruction include (1) the child reconstruction defined as pancreatojejunostomy/PJ followed by hepaticojejuno...
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Long-Term Quality of Life Assessment After Successful Endoscopic Vacuum Therapy of Defects in the Upper Gastrointestinal Tract Quality of Life After EVT
Accumulating evidence indicates that anastomotic leakages and perforations of the upper gastrointestinal tract (uGIT) can be treated successfully with endoscopic vacuum therapy (EVT). So far, no data is availa...
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Article
Therapie des Rektumkarzinoms — ein Update
Dank optimierter chirurgischer und multimodaler Therapiekonzepte konnte die Prognose beim Rektumkarzinom über die vergangenen Jahrzehnte stark verbessert werden. Lesen Sie im Folgenden, was sich im Hinblick au...
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Article
Esophageal achalasia and pregnancy: own observations in 43 patients and a review of the literature
Little is known concerning the interaction of achalasia and pregnancy and about an optimal time and type for treatment. Achalatic women of our collective of patients with at least one pregnancy in their histor...
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Article
Non-loose unknots, overtwisted discs, and the contact map** class group of S3
We classify Legendrian unknots in overtwisted contact structures on S3. In particular, we show that up to contact isotopy for every pair ...
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Article
Open AccessIdiosyncratic Drug-Induced Severe Neutropenia and Agranulocytosis in Elderly Patients (≥75 years): A Monocentric Cohort Study of 61 Cases
Little data is currently available in the literature on neutropenia and agranulocytosis in the elderly, and, to our knowledge, idiosyncratic drug-induced agranulocytosis is particularly poorly covered, or not ...
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Article
Load-bearing behavior of spliced glass beams under bending action
The load-bearing behavior of spliced structural glass beams under bending action is investigated using FE simulations. Since geometric singularities occur in spliced structural glass beams, stress concentratio...
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Article
Open AccessPartnerships in global health and collaborative governance: lessons learnt from the Division of Tropical and Humanitarian Medicine at the Geneva University Hospitals
In 2007 the “Crisp Report” on international partnerships increased interest in Northern countries on the way their links with Southern partners operated. Since its establishment in 2007 the Division of Tropica...
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Open AccessHealth benefits of cycle ergometer training for older adults over 70: a review
As the number of older adults continues to increase worldwide, more attention is being paid to geriatric health care needs, and successful ageing is becoming an important topic in the medical literature. A pre...
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Reliability of sensor-based real-time workflow recognition in laparoscopic cholecystectomy
Laparoscopic cholecystectomy is a very common minimally invasive surgical procedure that may be improved by autonomous or cooperative assistance support systems. Model-based surgery with a precise definition o...