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  1. No Access

    Article

    Identification of three histone methyltransferases in Drosophila: dG9a is a suppressor of PEV and is required for gene silencing

    Organization of chromatin structure and regulation of gene transcription are contingent on histone tail modifications. Regions of the genome packaged with nucleosomes that contain methyl histone H3 at lysine 9...

    Jacek Mis, Sarbjit S. Ner, Thomas A. Grigliatti in Molecular Genetics and Genomics (2006)

  2. No Access

    Article

    Characterization of mutations that enhance position-effect variegation in Drosophila melanogaster

    Several mutants that enhance the gene inactivation associated with position-effect variegation [E(var) mutants] have been characterized. These include three ethyl methanesulfonate (EMS)-induced lesions and a seco...

    Donald A. R. Sinclair, Vett K. Lloyd… in Molecular and General Genetics MGG (1989)

  3. No Access

    Article

    Regulation of dosage compensation in X-chromosomal trisomies of Drosophila melanogaster

    In this study, we provide evidence which supports the possibility that dosage compensation in X-chromosomal trisomies (metafemales) can occur by a mechanism distinct from the regulatory system that operates to...

    Robert H. Devlin, David G. Holm, Thomas A. Grigliatti in Molecular and General Genetics MGG (1985)

  4. No Access

    Article

    Genes which suppress position-effect variegation in Drosophila melanogaster are clustered

    We have isolated more than 50 dominant suppressors and 3 dominant enhancers of position effect variegation in Drosophila melanogaster. To our surprise, genetic map** studies revealed that the Su(var) mutations ...

    Donald A. R. Sinclair, Randall C. Mottus… in Molecular and General Genetics MGG (1983)

  5. No Access

    Article

    RNA-DNA hybridization analyses of tRNA 3b Val in Drosophila melanogaster

    Transfer RNA was extracted from 50–300 mg of adult flies and specifically labeled in vitro. The level of individual isoacceptors was quantitated by efficient annealing to Drosphila tRNA genes carried on recombina...

    Trina M. Larsen, Robert C. Miller Jr.… in Molecular and General Genetics MGG (1982)

  6. No Access

    Article

    Temperature-sensitive mutations in Drosophila melanogaster

    Improved methods for rearing and screening large numbers of flies permitted the recovery of 10 mutations exhibiting a reversible temperature-dependent adult paralysis among 1.1×106 flies tested. Of the 10 mutatio...

    Thomas A. Grigliatti, Linda Hall, Raja Rosenbluth… in Molecular and General Genetics MGG (1973)