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  1. Article

    Open Access

    Involvement of orexin neurons in fasting- and central adenosine-induced hypothermia

    We examined whether orexin neurons might play a protective role against fasting- and adenosine-induced hypothermia. We first measured body temperature (BT) in orexin neuron-ablated (ORX-AB) mice and wild-type ...

    Takahiro Futatsuki, Akira Yamashita, Khairunnisa Novita Ikbar in Scientific Reports (2018)

  2. Article

    Open Access

    Circulating activated protein C levels are not increased in septic patients treated with recombinant human soluble thrombomodulin

    Recombinant human soluble thrombomodulin (rTM) has been used for the treatment of disseminated intravascular coagulation in Japan, and an international phase III clinical trial for rTM is currently in progress...

    Takuro Arishima, Takashi Ito, Tomotsugu Yasuda, Nozomi Yashima in Thrombosis Journal (2018)