13 Result(s)

Article

PRRG4 regulates mitochondrial function and promotes migratory behaviors of breast cancer cells through the Src-STAT3-POLG axis

Breast cancer is the leading cause of cancer death for women worldwide. Most of the breast cancer death are due to disease recurrence and metastasis. Increasingly accumulating evidence indicates that mitochond...

Yang Wang, Jieyi Wang, Lan Chen, Zhuo Chen, Tong Wang… in Cancer Cell International (2023)

Article

The potential of using blood circular RNA as liquid biopsy biomarker for human diseases

Circular RNA (circRNA) is a novel class of single-stranded RNAs with a closed loop structure. The majority of circRNAs are formed by a back-splicing process in pre-mRNA splicing. Their expression is dynamicall...

Guoxia Wen, Tong Zhou, Wanjun Gu in Protein & Cell (2021)

Article

Cooperation-based sperm clusters mediate sperm oviduct entry and fertilization

Yongcun Qu, Qi Chen, Shanshan Guo, Chiyuan Ma, Yonggang Lu, Junchao Shi… in Protein & Cell (2021)

Article

Correction to: Expression and prognostic significance of CBX2 in colorectal cancer: database mining for CBX family members in malignancies and vitro analyses

He Zhou, Yongfu **ong, Zuoliang Liu, Songlin Hou, Tong Zhou in Cancer Cell International (2021)

Article

The requirement of mitochondrial RNA polymerase for non-small cell lung cancer cell growth

POLRMT (RNA polymerase mitochondrial) is responsible for the transcription of mitochondrial genome encoding key components of oxidative phosphorylation. This process is important for cancer cell growth. The cu...

Tong Zhou, Yong-Hua Sang, Shang Cai, Chun Xu, Min-hua Shi in Cell Death & Disease (2021)

Article

Expression and prognostic significance of CBX2 in colorectal cancer: database mining for CBX family members in malignancies and vitro analyses

The Chromobox (CBX) domain protein family, a core component of polycomb repressive complexes 1, is involved in transcriptional repression, cell differentiation, and program development by binding to methylated...

He Zhou, Yongfu **ong, Zuoliang Liu, Songlin Hou, Tong Zhou in Cancer Cell International (2021)

Article

Author Correction: PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications

A Correction to this paper has been published: https://doi.org/10.1038/s41556-021-00687-w.

Junchao Shi, Yunfang Zhang, Dongmei Tan, Xudong Zhang, Menghong Yan… in Nature Cell Biology (2021)

Article

mTOR-Myc axis drives acinar-to-dendritic cell transition and the CD4⁺ T cell immune response in acute pancreatitis

The inflammatory response in acute pancreatitis (AP) is associated with acinar-to-dendritic cell transition. The CD4⁺ T-cell-mediated adaptive immune response is necessary for pancreatic inflammatory damage. Howe...

Dan Xu, Rongli **e, Zhiwei Xu, Zhifeng Zhao, Min Ding, Wei Chen… in Cell Death & Disease (2020)

Article

Upregulation of SLAMF3 on human T cells is induced by palmitic acid through the STAT5-PI3K/Akt pathway and features the chronic inflammatory profiles of type 2 diabetes

Metabolic stress-induced low-grade chronic inflammation plays an important role in the development of insulin-resistance and type 2 diabetes (T2D). Emerging evidence highlights the importance of directly eluci...

Tong Zhou, Guixia Wang, Yanan Lyu, Lei Wang, Siyao Zuo, Jun Zou… in Cell Death & Disease (2019)

Article

Oncogenic effect of PHLDB2 is associated with epithelial–mesenchymal transition and E-cadherin regulation in colorectal cancer

Pleckstrin Homology Like Domain Family Member 2 (PHLDB2) is an important protein with a PH-domain for interaction with partners to regulate cell migration. However, the role of PHLDB2 in human cancer metastasi...

Geng Chen, Tong Zhou, Tantan Ma, Tingting Cao, Zhenxiang Yu in Cancer Cell International (2019)

Article

Glutathione prevents chronic oscillating glucose intake-induced β-cell dedifferentiation and failure

Modern lifestyles have altered diet and metabolic homeostasis, with increased sugar intake, glycemic index, and prediabetes. A strong positive correlation between sugar consumption and diabetic incidence is re...

Jitai Zhang, Hui An, Kaidi Ni, Bin Chen, Hui Li, Yanqin Li… in Cell Death & Disease (2019)

Article

An assessment of prognostic immunity markers in breast cancer

Tumor-infiltrating lymphocytes (TIL) and immunity gene signatures have been reported to be significantly prognostic in breast cancer but have not yet been applied for calculation of risk of recurrence in clini...

Benlong Yang, Jeff Chou, Yaozhong Tao, Dengbin Wu, **nhong Wu… in npj Breast Cancer (2018)

Article

Up-regulation of miR-224 promotes cancer cell proliferation and invasion and predicts relapse of colorectal cancer

MicroRNAs (miRNAs) are small, non-coding RNAs that can function as oncogenes or tumor suppressors in human cancer. Abnormally expressed miR-224 was found to play a fundamental role in several types of cancer. ...

Guang-jun Zhang, He Zhou, Hua-xu **ao, Yu Li, Tong Zhou in Cancer Cell International (2013)